1,1'-bis(phenoxymethyl)ferrocene | 186412-12-4

• 英文名称: 1,1'-bis(phenoxymethyl)ferrocene
• CAS: 186412-12-4
• 化学式: C₂₄H₂₂FeO₂
• 分子量: 398.284
• InChiKey: IMMYMXFOPCCHNT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  1,1′-bis(N,N′-dimethylaminomethyl)ferrocene 、 苯酚 在 sodium hydride 作用下， 以 乙腈 为溶剂， 以50%的产率得到1,1'-bis(phenoxymethyl)ferrocene
  参考文献：
  名称：

  A simple high-yielding synthesis of ferrocene-1,′-diylbis-(methyltrimethylammonium iodide)

  摘要：

  A new simple, high-yielding procedure has been developed for the synthesis of ferrocene-1, 1'-diylbis(methyltrimethylammonium iodide) 2. Ferrocene is dilithiated using n-butyllithium/TMEDA and then reacted with Eschenmoser's salt to form the bis(dimethylaminomethyl) derivative 6 in good yield. Treatment with iodomethane gives rise to the corresponding ammonium salt 2 in excellent yield. Reaction of this bis-ammonium salt with sodium phenoxide affords the 1, 1'-bis(phenoxymethyl) compound 10.

  DOI：

  10.1016/s0022-328x(96)06644-2