(ethanolammonium)[diphenyl((2-(5-carboxypyridyl))-carbonyloxy-O,N)borinate] | 1361544-37-7

• 英文名称: (ethanolammonium)[diphenyl((2-(5-carboxypyridyl))-carbonyloxy-O,N)borinate]
• CAS: 1361544-37-7
• 化学式: C₂H₇NO*C₁₉H₁₄BNO₄
• 分子量: 392.219
• InChiKey: LMQOHAXJOJKPKW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  2,5-二吡啶羧酸 、 二苯基酸 在 甲醇 作用下， 以80%的产率得到(ethanolammonium)[diphenyl((2-(5-carboxypyridyl))-carbonyloxy-O,N)borinate]
  参考文献：
  名称：

  Novel boron compounds of 2,3- and 2,5-pyridinedicarboxylic acids

  摘要：

  The (Hea)[B(ph)(2)(2,3-pydc)] (1) and (Hea)[B(ph)(2)(2,5-pydc)] (2) boron compounds (2,3-H(2)pydc = 2,3-pyridinedicarboxylic acid, 2,5-H(2)pydc = 2,5-pyridinedicarboxylic acid, Hea = ethanolammonium) were synthesized and characterized by elemental analysis, spectroscopic measurements (UV-Vis, B-11 NMR, C-13 NMR, H-1 NMR and IR spectra) and single crystal X-ray diffraction technique. Compound 1 and 2 crystallize in the monoclinic space group P2(1)/c. The crystal packing of compound 1 is stabilized through strong intermolecular hydrogen bonding and C-H center dot center dot center dot pi interactions, resulting in a 3D framework. The individual molecules of 2 are connected by the N-H center dot center dot center dot O and O-H center dot center dot center dot O hydrogen bonds leading to two-dimensional hydrogen bonded layer. The in vitro antibacterial and anticandidal activities of (1) and (2) were evaluated by disc diffusion method and MIC tests. Both new complexes showed antimicrobial activity against MRSA and clinical and standard yeast isolates. (C) 2011 Elsevier B. V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.11.006