cis-[platinum(II)dichloride(PN3C6H12(CH2)4SO3)2] | 1430837-95-8

• 英文名称: cis-[platinum(II)dichloride(PN3C6H12(CH2)4SO3)2]
• CAS: 1430837-95-8
• 化学式: C₂₀H₄₀Cl₂N₆O₆P₂PtS₂
• 分子量: 852.64
• InChiKey: FKKKSFXZMVYEEK-DKYDGWPBSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  1,3,5-三氮杂-7-磷杂金刚烷 以 乙醇 为溶剂， 反应 20.0h， 生成 cis-[platinum(II)dichloride(PN3C6H12(CH2)4SO3)2]
  参考文献：
  名称：

  New PTA (1,3,5-triaza 7-phosphaadamantane) derivatives associating zwitterionic structure and coordinative ability

  摘要：

  The reactions of PTA (1,3,5-triaza 7-phosphaadamantane) and HMTA (1,3,5,7-tetraazaadamantane) with 1,3-propanesultone or 1,4-butanesultone gave the water soluble zwitterionic derivatives PTA(+) C3H6SO3 (1), PTA+ C4H8SO3 (2), HMTA(+) C3H6SO3 (3) and HMTA(+)C(4)H(8)SO(3) (4). The crystal structure of HMTA(+)C(3) H6SO3 is reported. The coordinative ability of 1-4 towards Pt(II) and Ru(II) has been investigated and the antiproliferative activity of ligands and complexes has been tested in two human ovarian cancer cell lines, A2780 and SKOV3. (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2012.12.006