1,2-bis(4-bromophenyl)-1,1,2,2-tetrafluoroethane | 2378-49-6

• 英文名称: 1,2-bis(4-bromophenyl)-1,1,2,2-tetrafluoroethane
• 英文别名: 1,1,2,2-Tetrafluoro-1,2-bis(4-bromophenyl)ethane；1-bromo-4-[2-(4-bromophenyl)-1,1,2,2-tetrafluoroethyl]benzene
• CAS: 2378-49-6
• 化学式: C₁₄H₈Br₂F₄
• 分子量: 412.019
• InChiKey: FJBQHJSARLROEP-UHFFFAOYSA-N

物化性质

• 熔点：
  99-100 °C
• 沸点：
  367.4±42.0 °C(Predicted)
• 密度：
  1.725±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.9
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  4,4'-二溴联苯酰 在 F₆Mo 、 三氟化硼 作用下， 以 二氯甲烷 为溶剂， 生成 1,2-bis(4-bromophenyl)-1,1,2,2-tetrafluoroethane
  参考文献：
  名称：

  六氟甲醛和醛与丙酮的反应

  摘要：

  取代基F，Cl，Br，CN，NO 2，COOR，CONR 2，P（O）R 2不会干扰MoF 6与芳族醛和酮的反应，生成宝石二氟化合物，但会破坏OH，NH或OR ，NR 2，CC优先与MoF 6反应并阻止在CO处反应。通过在羰基衍生物上吸引电子的取代基提高了Ge-difluoro化合物的收率，并在空间上阻碍了CO基团时降低了收率。RCF 2 R'化合物的水解稳定性随R和R'的性质而变化很大。对R和R'的一些反应使CF 2基团不受影响。因此，许多新的CF 2化合物制备包括α，α-二氟烷基取代的苄基醇32苄34,36苯甲醛27，苯甲酸24，28，31，35。给出了所有新衍生物的1 H和19 F NMR数据。转换的机制暂定。

  DOI：

  10.1016/0040-4020(75)80050-0

文献信息

• Direct addition of fluorine to arylacetylenes
  作者：Julia Gatenyo、Shlomo Rozen

  DOI：10.1016/j.jfluchem.2008.12.009

  日期：2009.3

  Under suitable conditions elemental fluorine can be added across the carbon–carbon triple bond of arylacetylenes forming tetrafluoroethane derivatives – ArCF2CF2R – in good yields.

  ARCF -在合适的条件元素氟可以跨越形成四氟乙烷衍生物arylacetylenes的碳-碳三键可以添加2 CF 2的R -以良好的收率。
• Silver-catalyzed decarboxylative homocoupling reaction for the construction of tetrafluoroethylene-bridging aromatic compounds
  作者：Yong Wang、Huaxin Zhao、Xiaojuan Xie、Haizhen Jiang、Hongmei Deng、Jian Hao、Wen Wan

  DOI：10.1080/00397911.2019.1651865

  日期：——

  Abstract The Ag(I)-catalyzed decarboxylative homocoupling from the difluoroacetate has been developed to the synthesis of symmetric CF2–CF2 containing dimers. This radical dimerization overpasses the prefunctionalization of the substrate and provides a direct and efficient method for construction of tetrafluoroethylene bridge-linked homodimers. GRAPHICAL ABSTRACT

  摘要 Ag(I) 催化的二氟乙酸酯脱羧均偶联已被开发用于合成含有二聚体的对称 CF2-CF2。这种自由基二聚反应超越了底物的预官能化，为构建四氟乙烯桥联同二聚体提供了一种直接有效的方法。图形概要
• Direct nucleophilic fluorination of carbonyl groups of benzophenones and benzils with Deoxofluor
  作者：Ying Chang、Amit Tewari、Avi-Izak Adi、Chulsung Bae

  DOI：10.1016/j.tet.2008.08.009

  日期：2008.10

  The carbonyl groups of diaryl ketones and diaryl diketones were directly fluorinated with bis(2-methoxyethyl)aminosulfur trifluoride (Deoxofluor) under neat conditions to give the Corresponding gem-difluorides and tetrafluorinated derivatives in moderate to high yields. (C) 2008 Elsevier Ltd. All rights reserved.
• Malichenko,B.F.; Yagupol'skii,L.M., Journal of general chemistry of the USSR, 1964, vol. 34, p. 1232 - 1236
  作者：Malichenko,B.F.、Yagupol'skii,L.M.

  DOI：——

  日期：——
• FLUORINATED AROMATIC POLYMER AND METHOD FOR PRODUCING SAME
  申请人：DAIKIN INDUSTRIES, LTD.

  公开号：US20210253786A1

  公开（公告）日：2021-08-19

  The present invention addresses the problem of providing a fluorine-containing aromatic polymer; a method for producing the fluorine-containing aromatic polymer; etc. The problem can be solved by: a polymer having a monomer unit represented by formula (1) (wherein R 1 in each occurrence is independently a halogen atom, NR 11 R 12 (wherein R 11 and R 12 are independently a hydrogen atom or an organic group), or an organic group; n1 is an integer of 0 to 4; two R 1 s that can be present in the ortho-positions may form a ring together with two carbon atoms on the adjacent benzene ring, wherein the formed ring may have an organic group as a substituent; and L 1 is a single bond, an oxygen atom, a sulfur atom, -L 11 -O—, —O-L 12 -O—, -L 13 -S—, or —S-L 14 -S— (wherein L 11 to L 14 are each independently an alkylene group optionally having one or more substituents); etc.