[Zn(1,3-bis(2-pyridylmethylthio)propane)Cl2] | 1341124-24-0

• 英文名称: [Zn(1,3-bis(2-pyridylmethylthio)propane)Cl2]
• CAS: 1341124-24-0
• 化学式: C₁₅H₁₈Cl₂N₂S₂Zn
• 分子量: 426.749
• InChiKey: LYQGQLJGZPRGDX-UHFFFAOYSA-L

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  1,3-bis(2-pyridylmethylthio)propane 、 zinc(II) chloride 以 乙醇 为溶剂， 以0%的产率得到[Zn(1,3-bis(2-pyridylmethylthio)propane)Cl2]
  参考文献：
  名称：

  Zinc(II) complexes of 1,3-bis(2-pyridylmethylthio)propane: Anion dependency, crystal structure and DNA binding study

  摘要：

  Zinc(II) complexes of the formula [Zn(L)(X)(2)] (where X = Cl-, N-3(-), NCO- and SCN- (1a-d, respectively)) and {[Zn(L)(ClO4)(H2O)](ClO4)}(n) (2), were isolated in the pure form on the reaction of 1,3-bis(2-pyridylmethylthio)propane (L) with different zinc(II) salts. All the complexes were characterized by physicochemical and spectroscopic tools. The X-ray crystallographic analyses of the complexes id and 2 showed that the former is mononuclear while complex 2 is a 1D coordination polymer, {[Zn(L)(ClO4)(H2O)](ClO4)}(n) due to a different coordination mode of the tetradentate ligand L. The zinc(II) ions present an octahedral coordination geometry in both compounds, which is more distorted in the mononuclear complex 1d. The study indicates that the counter anion of the zinc(II) salt used as reactant leads to a different type of complex when isolated as a crystalline material. A spectroscopic study of the interaction of complex, 2 with calf thymus-DNA (CT-DNA) in Tris-HCl buffer showed a significant non-intercalative interaction with a binding constant (K-b) of 4.7 x 10(4) M-1, and the linear Stern-Volmer quenching constant (K-sv) and the binding sites (n) were found to be 1.3 x 10(3) and 0.92 respectively, calculated from ethidium bromide (EB) fluorescence displacement experiments. (C) 2011 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.poly.2011.08.025