Au(III)(nicotinamide)Cl3 | 1391864-72-4

• 英文名称: Au(III)(nicotinamide)Cl3
• 英文别名: Au(vitamin B3)Cl3
• CAS: 1391864-72-4
• 化学式: C₆H₆AuCl₃N₂O
• 分子量: 425.452
• InChiKey: NFXPTVINTRLSGB-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  sodium tetrachloroaurate(III) dihyrate 、 烟酰胺 以 甲醇 、 水 为溶剂， 生成 Au(III)(nicotinamide)Cl3
  参考文献：
  名称：

  Ten metal complexes of vitamin B3/niacin: Spectroscopic, thermal, antibacterial, antifungal, cytotoxicity and antitumor studies of Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Pd(II), Cd(II), Pt(IV) and Au(III) complexes

  摘要：

  Ten coordination compounds, namely Mn(NA)(2)Cl-2 center dot 4H(2)O (1), Fe(NA)Cl-3(H2O)(2) (2), Co(NA)(2)(NO3)(2)center dot 6H(2)O (3), Ni(NA)Cl-2 center dot 5H(2)O (4), Cu(NA)Cl-2 center dot 3H(2)O (5), Zn(NA)(NO3)(2)center dot H2O (6), Pd(NA)(2)Cl-2 center dot H2O (7), Cd(NA)Cl-2 center dot H2O (8), Pt(NA)(2)Cl-4 center dot 5H(2)O (9) and Au(NA)Cl-3 (10) were obtained by the reactions of the corresponding transition metal salts with vitamin B3/niacin (NA) in the presence of 1:4 (v:v) distilled water: methanol solvent at 70 degrees C for about 30 min, and their suggested structures were determined by elemental analyses, molar conductivity, (infrared, UV-vis) spectra, effective magnetic moment in Bohr magnetons, electron spin resonance (ESR), thermal analysis (TG), X-ray powder diffraction (XRD) as well as scanning electron microscopy (SEM). The results revealed that in complexes 1, 3, 7, and 9 both of two NA ligand coordinates one metal ion to form four or six coordinated structures, while in compound 10, one NA ligand coordinate to Au+++ ion to form a square-planar geometry with N-bonded pyridine ligand is suggested, and (2, 4, 5, 6 and, 8) complexes have 1:1 structures. Antimicrobial and antitumor activities were assessment against some kind of (G(+) and G(-)) bacteria, fungi and breast carcinoma cells (MCF-7-cell line). (C) 2012 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.molstruc.2012.04.057