[Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl2] | 889061-82-9

• 英文名称: [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl2]
• CAS: 889061-82-9
• 化学式: C₁₉H₁₅Cl₂CoN₃O₂
• 分子量: 447.246
• InChiKey: DJTCPAMRLWTCMM-LSLBEZLLSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl2] 以 neat (no solvent) 为溶剂， 生成 cobalt(II) oxide
  参考文献：
  名称：

  Synthesis, characterization and biological activity of bis(phenylimine) Schiff base ligands and their metal complexes

  摘要：

  Metal complexes derived from 2,6-pyridinedicarboxaldehydebis(p-hydroxyphenylimine); L-1, 2,6-pyfidinedicarboxaldehydebis (o-hydroxyphenylimine); L-2, are reported and characterized based on elemental analyses, IR, solid reflectance, magnetic moment, molar conductance and thermal analysis (TGA). The complexes are found to have the formulae [MX2(L-1 or L-2)](.)nH(2)O, where M = Fe(II), Co(II), Ni(II), Cu(II) and Zn(II), X = Cl in case of Fe(II), Co(II), Ni(II), Cu(II) complexes and Br in case of Zn(II) complexes and n = 0-2.5. The molar conductance data reveal that the chelates are non-electrolytes. IR spectra show that the Schiff bases are coordinated to the metal ions in a terdentate manner with NNN donor sites of the pyridine-N and two azomethine-N. From the magnetic and solid reflectance spectra, it is found that the geometrical structure of these complexes are trigonal bipyramidal (in case of Co(II), Ni(II), Cu(II) and Zn(II) complexes) and octahedral (in case of Fe(II) complexes). The thermal behaviour of these chelates shows that the hydrated complexes losses water molecules of hydration in the first step followed immediately by decomposition of the coordinated water, anions and ligands (L-1 and L-2) in the subsequent steps. The activation thermodynamic parameters, such as, E*, Delta H*, Delta S* and Delta G* are calculated from the TG curves using Coats-Redfern method. The synthesized ligands, in comparison to their metal complexes also were screened for their antibacterial activity against bacterial species, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Fungi (Candida). The activity data show that the metal complexes to be more potent/antibacterial than the parent organic ligands against one or more bacterial species. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2005.05.044
• 作为产物：
  描述：

  [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl2]*2.5H2O 以 neat (no solvent) 为溶剂， 生成 [Co(2,6-pyridinedicarboxaldehydebis(o-hydroxyphenylimine))Cl2]
  参考文献：
  名称：

  Synthesis, characterization and biological activity of bis(phenylimine) Schiff base ligands and their metal complexes

  摘要：

  Metal complexes derived from 2,6-pyridinedicarboxaldehydebis(p-hydroxyphenylimine); L-1, 2,6-pyfidinedicarboxaldehydebis (o-hydroxyphenylimine); L-2, are reported and characterized based on elemental analyses, IR, solid reflectance, magnetic moment, molar conductance and thermal analysis (TGA). The complexes are found to have the formulae [MX2(L-1 or L-2)](.)nH(2)O, where M = Fe(II), Co(II), Ni(II), Cu(II) and Zn(II), X = Cl in case of Fe(II), Co(II), Ni(II), Cu(II) complexes and Br in case of Zn(II) complexes and n = 0-2.5. The molar conductance data reveal that the chelates are non-electrolytes. IR spectra show that the Schiff bases are coordinated to the metal ions in a terdentate manner with NNN donor sites of the pyridine-N and two azomethine-N. From the magnetic and solid reflectance spectra, it is found that the geometrical structure of these complexes are trigonal bipyramidal (in case of Co(II), Ni(II), Cu(II) and Zn(II) complexes) and octahedral (in case of Fe(II) complexes). The thermal behaviour of these chelates shows that the hydrated complexes losses water molecules of hydration in the first step followed immediately by decomposition of the coordinated water, anions and ligands (L-1 and L-2) in the subsequent steps. The activation thermodynamic parameters, such as, E*, Delta H*, Delta S* and Delta G* are calculated from the TG curves using Coats-Redfern method. The synthesized ligands, in comparison to their metal complexes also were screened for their antibacterial activity against bacterial species, Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureus and Fungi (Candida). The activity data show that the metal complexes to be more potent/antibacterial than the parent organic ligands against one or more bacterial species. (c) 2005 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.saa.2005.05.044