[Au(dipyrido[3,2-a:2′,3′-c]phenazine)Cl₂]Cl | 933036-79-4

• 英文名称: [Au(dipyrido[3,2-a:2′,3′-c]phenazine)Cl₂]Cl
• 英文别名: [Au(dppz)Cl₂]Cl；[Au(dipydido[a,c]phenazine)Cl2]Cl
• CAS: 933036-79-4
• 化学式: C₁₈H₁₀AuCl₂N₄*Cl
• 分子量: 585.63
• InChiKey: RJABYMIZCFIDFM-UHFFFAOYSA-K

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  二吡啶并[3,2-a:2',3'-c]吩嗪 、 chloroauric acid 以 水 、 乙腈 为溶剂， 以60%的产率得到[Au(dipyrido[3,2-a:2′,3′-c]phenazine)Cl₂]Cl
  参考文献：
  名称：

  Spectroscopic and electrochemical properties of dichlorodiimine complexes of Au(III) and Pt(II) with 1,4-diazine derivatives of o-phenanthroline

  摘要：

  A series of dichlorodiimine complexes [M(N boolean AND N)Cl-2](z) of Au(III) and Pt(II) with 1,4-derivatives of o-phenanthroline [(N boolean AND N) = o-phenanthroline (phen), dipyrido[f,h]quinoxaline (dpq), dipyrido[a,c]phenazine (dppz), 6,7-dicyanodipyrido[f,h]quinoxaline (dicnq)] were prepared and characterized by H-1 NMR, electronic absorption, and emission spectroscopy and by cyclic voltammetry. In all the complexes, the (3)(pi-pi*)-type transition is the spin-forbidden transition of the lowest energy, responsible for the luminescence. The longest wave bands in the absorption spectra of the Au(III) and Pd(II) complexes were assigned in accordance with the results of the electrochemical studies to the (1)(pi-d*)- and (1)(d-pi*)-type transitions, respectively.

  DOI：

  10.1134/s1070363206060016

文献信息

• The in vitro assessment of dipyridophenazine complexes in H-ras oncogene transformed rat embryo fibroblast 5RP7 cell line
  作者：Ayse Kaplan、Kadriye Benkli、Ayse Tansu Koparal

  DOI：10.1007/s10637-017-0559-4

  日期：2018.10

  and its metal derivatives. The substances were investigated by using an h-ras oncogene transformed rat embryo fibroblast cell line (5RP7). Methods The cytotoxic influences of dipyrido[3,2-a:2',3'c]phenazine ligand, dipyrido[3,2-a:2',3'c] phenazine-platinum(II) complex ([Pt(dppz)Cl2]) and dipyrido[3,2-a:2',3'c] phenazine-gold(III) complex ([Au(dppz)Cl2]Cl) were determined with MTT (3[4,5-dimetiltiyazol2-yl]-2

  目的这项研究的目的是检测配体物质及其金属衍生物的凋亡和细胞毒性/抗增殖作用。通过使用h-ras致癌基因转化的大鼠胚胎成纤维细胞系（5RP7）研究了这些物质。方法：二吡啶并[3,2-a：2'，3'c]吩嗪配体，二吡啶并[3,2-a：2'，3'c]吩嗪-铂（II）复合物（[Pt（dppz ）Cl2]）和二吡啶[3,2-a：2'，3'c]吩嗪-金（III）配合物（[Au（dppz）Cl2] Cl）用MTT（3 [4,5-dimetiltiyazol2- yl] -2,5-difeniltetrazolyum bromid）对5RP7细胞的检测。结果Dipyrido [3,2-a：2'，3'c]吩嗪，双嘧啶[3,2-a：2'，3'c]吩嗪-铂（II）配合物（[Pt（dppz）Cl2]）和dipyrido [3,2-a：2'，3' c]吩嗪-金（III）配合物（[Au（dppz）Cl2] Cl）以剂