5,6-Bis(3-acetylanilino)pyridine-2,3-dione | 660398-94-7

• 英文名称: 5,6-Bis(3-acetylanilino)pyridine-2,3-dione
• 英文别名: 5-(3-acetylanilino)-6-(3-acetylphenyl)iminopyridine-2,3-dione
• CAS: 660398-94-7
• 化学式: C₂₁H₁₇N₃O₄
• 分子量: 375.4
• InChiKey: FMWSDZWYKBBLRY-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  28
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  105
• 氢给体数：
  2
• 氢受体数：
  5

文献信息

• O-pyridinequinone derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives
  申请人：Gu Lianquan

  公开号：US20060111405A1

  公开（公告）日：2006-05-25

  The present invention relates to the o-pyridinequinone disubstituted derivatives, the composition containing the derivatives, the process for preparation of the derivatives and the use of the derivatives. The o-pyridinequinone disubstituted derivatives of the present invention have action of selectivity inhibiting COX-2 and they can be made into pharmaceuticals. The o-pyridinequinone disubstituted derivatives of the present invention have no acute toxicities and are a safe pharmaceutical.

  本发明涉及o-吡啶醌二取代衍生物、含有该衍生物的组合物、制备该衍生物的过程以及该衍生物的用途。本发明的o-吡啶醌二取代衍生物具有选择性抑制COX-2的作用，可制成药物。本发明的o-吡啶醌二取代衍生物无急性毒性，是一种安全的药物。
• US7547713B2
  申请人：——

  公开号：US7547713B2

  公开（公告）日：2009-06-16