3-bromomethyl-7-oxo-8-phenyl-6-phenylsulfonyl-2,3,7,8-tetrahydro[1,3]thiazolo[3,2-a]pyrimidin-4-ium tribromide | 1137899-16-1

• 英文名称: 3-bromomethyl-7-oxo-8-phenyl-6-phenylsulfonyl-2,3,7,8-tetrahydro[1,3]thiazolo[3,2-a]pyrimidin-4-ium tribromide
• CAS: 1137899-16-1
• 化学式: Br₃*C₁₉H₁₆BrN₂O₃S₂
• 分子量: 704.096
• InChiKey: RFKVHLMOHKQNBW-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  2-allylsulfanyl-3-phenyl-5-(phenylsulfonyl)pyrimidin-4(3H)-one 在 溴 作用下， 以 氯仿 为溶剂， 反应 0.33h， 以71%的产率得到3-bromomethyl-7-oxo-8-phenyl-6-phenylsulfonyl-2,3,7,8-tetrahydro[1,3]thiazolo[3,2-a]pyrimidin-4-ium tribromide
  参考文献：
  名称：

  A convenient synthetic approach to derivatives of 5-phenylsulfonyl-2-thiouracil and its condensed analogs

  摘要：

  3-Amino-2-phenylsulfonylacrylonitrile, an available multicenter rea(yent when treated successively C I with phenyl, ethyl, or allyl isothiocyanate and hydrochloric acid forms N 3 -substituted 5-phenylsulfonylthiouracils. Some of them were found to be suitable starting mateials for preparing of thiazoline and thiodiazolidine structures fused with the 4-pyrimidone system.

  DOI：

  10.1134/s1070363208060194