2-(3-methyl-6-chlorophenoxy)-1-feroocenyl-2-(1H-1,2,4-trizol-1-yl)ethanone | 894429-20-0

• 英文名称: 2-(3-methyl-6-chlorophenoxy)-1-feroocenyl-2-(1H-1,2,4-trizol-1-yl)ethanone
• 英文别名: (ferrocenyl)COCH(N3C2H2)(3-Me-6-ClOC6H3)
• CAS: 894429-20-0
• 化学式: C₂₁H₁₈ClFeN₃O₂
• 分子量: 435.693
• InChiKey: YYUDLGNEUGTWJA-SQKCAUCHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  2-(3-methyl-6-chlorophenoxy)-1-feroocenyl-2-(1H-1,2,4-trizol-1-yl)ethanone 、 sodium tetrahydroborate 在 盐酸 作用下， 以 甲醇 、 乙腈 为溶剂， 以58.7%的产率得到(ferrocenyl)CHOHCH(N3C2H2)(3-Me-6-ClOC6H3)
  参考文献：
  名称：

  Synthesis and Biological Evaluation of Novel Ferrocene‐Substituted Triadimefon‐ and Triadimenol‐Analogues

  摘要：

  To search potent antifungal agents, a series of new ferrocene-containing analogues of commercial fungicides, namely triadimefon and triadimenol, were synthesized by replacement of the tert-butyl group of original agents with ferrocene group. These organometallic derivatives were found to be unactive against various fungi, but show promising plant growth regulatory activity.

  DOI：

  10.1080/15533170701608791
• 作为产物：
  描述：

  α-bromo-α-1H-1,2,4-triazol-1-yl-acetylferrocene 、 2-氯-5-甲酚 在 potassium carbonate 作用下， 以 乙腈 为溶剂， 以50.3%的产率得到2-(3-methyl-6-chlorophenoxy)-1-feroocenyl-2-(1H-1,2,4-trizol-1-yl)ethanone
  参考文献：
  名称：

  Synthesis, characterization, and biological evaluation of novel ferrocene-triadimefon analogues

  摘要：

  In order to improve biological behavior of the 1H-1,2,4-triazole derivatives, a series of new ferrocene-analogues of commercial triadimefon were synthesized and their antifungal and plant growth regulatory activities evaluated. These organometallic analogues showed lower antifungal activity than parent triadimefon, but exhibited promising plant growth regulatory activity. (c) 2005 Published by Elsevier B.V.

  DOI：

  10.1016/j.jorganchem.2005.11.029