[Ph3Sn(FcCOO)(H2O)]*phen | 1333901-11-3

• 英文名称: [Ph3Sn(FcCOO)(H2O)]*phen
• CAS: 1333901-11-3
• 化学式: C₁₂H₈N₂*C₂₉H₂₆FeO₃Sn
• 分子量: 777.29
• InChiKey: WWBMRIOIMAGOGE-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  1,10-菲罗啉 、 二茂铁甲酸 、 水 、 三苯基氯化锡 在 Me₄NOH 作用下， 以 甲醇 为溶剂， 以68%的产率得到[Ph3Sn(FcCOO)(H2O)]*phen
  参考文献：
  名称：

  Synthesis, characterization, crystal structure and antitumor activity of organotin(IV) compounds bearing ferrocenecarboxylic acid

  摘要：

  Four new organotin(IV) complexes [(Bu3Sn)(FcCOO)](n) (1), [(mu-Bu2Sn)(2)(mu-Bu(2)SnFcCOO)(2)(mu(3)-O)(2)(mu-OCH3)(2)](2) (2), [Ph3Sn(FcCOO)(H2O)](phen) (3) and [{Ph3Sn(FcCOO)}(2)(4,4'-bipy)] (4) [Fc = (eta(5)-C5H5)Fe(eta(5)-C5H4)] have been synthesized and characterized by elemental analyses, IR, (H-1 and C-13) NMR spectra and X-ray single-crystal diffraction analyses. The structure analyses show that all tin atoms in complexes 1-4 are five-coordinated with trigonal bipyramid geometry. Complexes 1-4 and FcCOOH undergo reversible one-electron oxidations in methanol solution. The antitumor activities of complexes 1-4 have also been tested. Complexes 1 and 2 exhibit medium activity towards P388 cell lines and Hela cell lines. Complexes 3 and 4 exhibit medium activity towards P388 cell lines but strong activity towards Hela cell lines. This may result from complexes 3 and 4 including the neutral molecules 1,10-phenanthroline and 4,4'-bipy. Crown Copyright (C) 2011 Published by Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.ica.2011.04.049