| 1597407-26-5

• CAS: 1597407-26-5
• 化学式: C₂₇H₂₆ClFN₂O₂RuS
• 分子量: 598.103
• InChiKey: VCFHSJPXYZNORL-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  RuCl(p-cymene)(2-phenylpyridine) 、 N-重氮基-4-氟苯磺酰胺 以 氘代甲醇 为溶剂， 生成
  参考文献：
  名称：

  Ruthenium-Catalyzed Direct C–H Amidation of Arenes: A Mechanistic Study

  摘要：

  We report mechanistic studies of C H activitation/amidation reactions using azides as the amino source catalyzed by [RuCl2(p-cymene)](2). We have achieved two intermediates in the catalytic cycle (C5H4NC6H4)Ru(p-cymene)Cl and (C5H4NC6H4)NArRu(p-cymene)Cl (Ar = NO2C6H4SO2). Furthermore, the process from (C5H4NC6H4)Ru(p-cymene)Cl to (C5H4NC6H4)NArRu(p-cymene)Cl was monitored by F-19 NMR and a ruthenium imido species was proposed to explain the formation of the azacyclopropane analogue.

  DOI：

  10.1021/om500080z