Pd(memantine)2Cl2 | 1607844-62-1

• 英文名称: Pd(memantine)2Cl2
• 英文别名: Pd(memantine)₂Cl₂
• CAS: 1607844-62-1
• 化学式: C₂₄H₄₂Cl₂N₂Pd
• 分子量: 535.937
• InChiKey: OTMKXKCAOSWLKU-FLYPJHGNSA-L

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  palladium diacetate 、 盐酸美金刚 以 二氯甲烷 为溶剂， 反应 4.0h， 以50%的产率得到Pd(memantine)2Cl2
  参考文献：
  名称：

  A highly efficient memantine-modified palladium catalyst for Suzuki–Miyaura cross-coupling reaction

  摘要：

  A new simple Pd(memantine)(2)Cl-2 complex was synthesized and characterized by H-1 NMR, C-13 NMR and X-ray single crystal structure determination. The Suzuki-Miyaura reaction of aryl bromides catalyzed by Pd(memantine)(2)Cl-2 complex was investigated in air with different temperature. The high turnover numbers of 650,000 have been obtained in the reaction of 4-bromonitrobenzene with phenylboronic acid at 80 degrees C. At room temperature, the complex also showed high activity for Suzuki-Miyaura cross-coupling reaction of aryl bromides with a wide range of functional groups under air, and the turnover number of up to 99,000 was achieved. The catalytic system also gives good yields toward the reaction of several heteroaryl bromides with thiophenylboronic acid. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.03.064
• 作为试剂：
  描述：

  2-溴吡啶 、 3-噻吩硼酸 在 Pd(memantine)2Cl2 、 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 24.0h， 以50%的产率得到2-(3-噻吩基)吡啶
  参考文献：
  名称：

  A highly efficient memantine-modified palladium catalyst for Suzuki–Miyaura cross-coupling reaction

  摘要：

  A new simple Pd(memantine)(2)Cl-2 complex was synthesized and characterized by H-1 NMR, C-13 NMR and X-ray single crystal structure determination. The Suzuki-Miyaura reaction of aryl bromides catalyzed by Pd(memantine)(2)Cl-2 complex was investigated in air with different temperature. The high turnover numbers of 650,000 have been obtained in the reaction of 4-bromonitrobenzene with phenylboronic acid at 80 degrees C. At room temperature, the complex also showed high activity for Suzuki-Miyaura cross-coupling reaction of aryl bromides with a wide range of functional groups under air, and the turnover number of up to 99,000 was achieved. The catalytic system also gives good yields toward the reaction of several heteroaryl bromides with thiophenylboronic acid. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.03.064