4-[3-(4-propoxy-phenoxy)-propyl]-morpholine | 93146-50-0

• 英文名称: 4-[3-(4-propoxy-phenoxy)-propyl]-morpholine
• 英文别名: 4-[3-(4-Propoxy-phenoxy)-propyl]-morpholin；4-[3-(4-Propoxyphenoxy)propyl]morpholine
• CAS: 93146-50-0
• 化学式: C₁₆H₂₅NO₃
• 分子量: 279.379
• InChiKey: ASEHBSPRNYEKRR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  20
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.62
• 拓扑面积：
  30.9
• 氢给体数：
  0
• 氢受体数：
  4

文献信息

• CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE
  申请人：Nocion Therapeutics, Inc.

  公开号：US20210309623A1

  公开（公告）日：2021-10-07

  The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are particularly useful for the treatment of itch and other dermal conditions.
• [EN] CHARGED ION CHANNEL BLOCKERS AND METHODS FOR USE<br/>[FR] BLOQUEURS DE CANAUX IONIQUES CHARGÉS ET LEURS PROCÉDÉS D'UTILISATION
  申请人：NOCION THERAPEUTICS INC

  公开号：WO2021183639A1

  公开（公告）日：2021-09-16

  The invention provides compounds of Formula (I), or pharmaceutically acceptable salts thereof. The compounds, compositions, methods and kits of the invention are particularly useful for the treatment of itch and other dermal conditions.