| 524935-55-5

• CAS: 524935-55-5
• 化学式: C₂HF₃O₂*C₁₇H₂₂FeN₂O₃
• 分子量: 472.244
• InChiKey: BMFUHQBWIMGEAO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  bis(2,2′-bipyridine)-4′-methyl-4-carboxybipyridine-ruthenium-N-succinimidyl ester-bis(hexafluorophosphate) 、 在 三乙胺 、 N,N'-二环己基碳二亚胺 作用下， 以 乙腈 为溶剂， 以76%的产率得到[Ru(bipy)2(4-carbonyl-4'-methyl-2,2'-bipyridyl-CONH(CH2)3C(COOCH3)NHC(O)-Fc](PF6)2
  参考文献：
  名称：

  A peptide approach to covalently linked [Ru(bipy)3]2+–ferrocene and [Ru(bipy)3]2+–tyrosine conjugates

  摘要：

  We have worked out the synthesis of two bifunctional photochemically active peptide derivatives based on a side chain ruthenium labeled amino acid. The ruthenium modified amino acid [H-Orn{Ru(bipy)(2)m}-OH](PF6)(3) (Orn = ornithine, in = 4-carbonyl-4'-methyl-2,2'-bipyridyl) was used as a module for the synthesis of a [Ru(bipy)(3)]-(Fc-CONHR) (Fc-CONHR = ferrocene-1-carboxamide), and a [Ru(bipy)(3)]-Tyr (Tyr = tyrosine) chromophore-quencher conjugate. The complex [Fc-Orn{Ru(bipy)(2)m}-OMe](PF6)(2) shows efficient luminescence quenching by energy transfer. Electron transfer from phenolate to ruthenium occurs in the dipeptide [Boc-Tyr-Orn{Ru(bipy)(2)m}-O](PF6) above pH 9. Implications for the development of cooperative sensing devices and light energy converting peptides are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01339-7
• 作为产物：
  描述：

  、 三氟乙酸 以 二氯甲烷 、 三氟乙酸 为溶剂， 生成
  参考文献：
  名称：

  A peptide approach to covalently linked [Ru(bipy)3]2+–ferrocene and [Ru(bipy)3]2+–tyrosine conjugates

  摘要：

  We have worked out the synthesis of two bifunctional photochemically active peptide derivatives based on a side chain ruthenium labeled amino acid. The ruthenium modified amino acid [H-Orn{Ru(bipy)(2)m}-OH](PF6)(3) (Orn = ornithine, in = 4-carbonyl-4'-methyl-2,2'-bipyridyl) was used as a module for the synthesis of a [Ru(bipy)(3)]-(Fc-CONHR) (Fc-CONHR = ferrocene-1-carboxamide), and a [Ru(bipy)(3)]-Tyr (Tyr = tyrosine) chromophore-quencher conjugate. The complex [Fc-Orn{Ru(bipy)(2)m}-OMe](PF6)(2) shows efficient luminescence quenching by energy transfer. Electron transfer from phenolate to ruthenium occurs in the dipeptide [Boc-Tyr-Orn{Ru(bipy)(2)m}-O](PF6) above pH 9. Implications for the development of cooperative sensing devices and light energy converting peptides are discussed. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)01339-7