pentacarbonyl(N-isopropyl-3,4-diphenyl-2-azetidin-1-ylidene)chromium | 252255-63-3

• 英文名称: pentacarbonyl(N-isopropyl-3,4-diphenyl-2-azetidin-1-ylidene)chromium
• CAS: 252255-63-3；252266-95-8
• 化学式: C₂₃H₁₉CrNO₅
• 分子量: 441.404
• InChiKey: KYKZYIZQJPBIKM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
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• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
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反应信息

• 作为产物：
  描述：

  N-苯亚甲基异丙醇胺 、 六羰基铬 、 苯乙炔 在 二氯甲烷 作用下， 以 二氯甲烷 为溶剂， 以33%的产率得到pentacarbonyl(N-isopropyl-3,4-diphenyl-2-azetidin-1-ylidene)chromium
  参考文献：
  名称：

  Synthesis of azetidinylidene complexes from [(CO)5M(CH2Cl2)], phenylacetylene and imines and oxidative decomplexation to give β-lactams

  摘要：

  Photolysis of [M(CO)(6)] in CH2Cl2 gives [(CO)(5)M(CH2Cl2)]. Substitution of phenylacetylene for CH2Cl2 produces the thermolabile phenylacetylene complexes [(CO)(5)M(HC=CPh)] [M=Cr (1), Mo (2), W (3)]. Addition of N-alkyl benzylideneimines, RN=C(Ph)H, to solutions of 1-3 affords the 2-azetidin-1-ylidene complexes [(CO)(5)M=C-NR-C(Ph)H-C(Ph)H] [M = Cr, Mo, W; R = Et, i-Pr]. The reaction presumably proceeds by cycloaddition of the imines to the C=C bond of vinylidene complexes resulting from tautomerization of the alkyne complexes. The cycloaddition is highly stereoselective. Predominantly, the syn isomer is obtained (syn/anti greater than or equal to 9). The reaction of 3 with dialkylcarbodimides, RN=C=NR (R=c-Hex, i-Pr), yields 3-imino-2-azetidinl-1-ylidene complexes, [(CO)(5)W=C-NR-C(=NR)-C(Ph)H]. By oxidative cleavage of the Cr=C bond in [(CO)(5)Cr=C-NR-C(Ph)H-C(Ph)H] the corresponding beta-lactams are obtained in high yields. (C) 1999 Elsevier Science S.A. All rights reserved.

  DOI：

  10.1016/s0022-328x(99)00381-2