8-[3α,17β-bis(acetyloxy)-2β-(4-acetyloxy-1-piperidinyl)-5α-androstan-16β-yl]-8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decane bromide | 159325-41-4

• 英文名称: 8-[3α,17β-bis(acetyloxy)-2β-(4-acetyloxy-1-piperidinyl)-5α-androstan-16β-yl]-8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decane bromide
• 英文别名: [1-[(2S,3S,5S,8R,9S,10S,13S,14S,16S,17R)-3,17-diacetyloxy-10,13-dimethyl-16-(8-methyl-1,4-dioxa-8-azoniaspiro[4.5]decan-8-yl)-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-2-yl]piperidin-4-yl] acetate;bromide
• CAS: 159325-41-4
• 化学式: Br*C₃₈H₆₁N₂O₈
• 分子量: 753.815
• InChiKey: ICHSFJBCQDINQB-XYDNWQIASA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.86
• 重原子数：
  49
• 可旋转键数：
  8
• 环数：
  7.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  101
• 氢给体数：
  0
• 氢受体数：
  10

文献信息

• Androstane derivatives substituted by a quaternary ammonium group in 16-position, pharmaceutical compositions containing them and process for preparing same
  申请人：Maruishi Pharmaceutical Co., Ltd.

  公开号：EP0608495B1

  公开（公告）日：1997-06-04
• US5591735A
  申请人：——

  公开号：US5591735A

  公开（公告）日：1997-01-07