[Pt((125)I-5-iodohistamine)Cl2]*2H2O | 461659-48-3

• 英文名称: [Pt((125)I-5-iodohistamine)Cl2]*2H2O
• CAS: 461659-48-3
• 化学式: C₅H₈Cl₂IN₃Pt
• 分子量: 501.125
• InChiKey: BDPGRUFLIRAFQD-SJSHTZRWSA-L

反应信息

• 作为产物：
  描述：

  potassium tetrachloroplatinate(II) 、 (125)I-5-iodohistamine 在 Na₂CO₃ 、 histamine 作用下， 以 水 为溶剂， 以70%的产率得到[Pt((125)I-5-iodohistamine)Cl2]*2H2O
  参考文献：
  名称：

  Synthesis and characterisation of platinum(II) complexes with histamine and iodohistamine

  摘要：

  New complexes of platinum(II) with histamine (Hist) and iodohistamine (lHist) have been synthesised and characterised by elemental analysis, mass spectrometry and chromatographic techniques. The structure of PtCl(2)Hist complex has been determined by single-crystal X-ray diffraction technique. The intermolecular NH...Pt and CH...Pt hydrogen bonds were observed. Radioactive analogues of PtCl(2)Hist or PtCl(2)IHist labelled with isotopes of iodine, i.e. I-125 or I-131 were prepared with the intention of potential application for concomitant anticancer radio-chemotherapy of solid tumours. (C) 2002 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(02)00980-5