1-([1-(dimethylamino)-1-methylethyl]phenyl)-3,4,4-trimethyl-1,2,3,4-tetrahydro-3,1-benzaazaborin | 258280-95-4

• 英文名称: 1-([1-(dimethylamino)-1-methylethyl]phenyl)-3,4,4-trimethyl-1,2,3,4-tetrahydro-3,1-benzaazaborin
• CAS: 258280-95-4
• 化学式: C₂₂H₃₁BN₂
• 分子量: 334.313
• InChiKey: YCVLFOLPMMSOPT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
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• 氢给体数：
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• 氢受体数：
  None

反应信息

• 作为产物：
  描述：

  硼酸三异丙酯 、 2-[1-(dimethylamino)-1-methylethyl]phenyllithium 以 乙醚 为溶剂， 以40%的产率得到1-([1-(dimethylamino)-1-methylethyl]phenyl)-3,4,4-trimethyl-1,2,3,4-tetrahydro-3,1-benzaazaborin
  参考文献：
  名称：

  Deprotonation from an N-Methyl Group in 2-[1-(Dimethylamino)-1-methylethyl]phenylborane Derivatives

  摘要：

  Reaction of 2-[1-(dimethylamino)-1-methylethyl]phenyllithiun (Ar*Li) with a trialkyl berate, B(OR)(3), in, the 3:1 ratio gave 1-Ar*-3,4,4-trimethyl-1,2,3,4-tetrahydro-3,1-benzazaborin. as a major product together. with the corresponding protonated compound and the boronic acid. The structure of the hetelocyclic compound was determined by X-ray analysis and NMR spectroscopy. This compound is formed via the deprotonation from one of the N-Me groups in. Ar*B-2(OR) by the remaining Ar*Li followed by the facile intramolecular cyclization between the boron and carbon, atoms.

  DOI：

  10.1021/om990724n