Pt(2,9-dimethyl-1,10-phenanthroline)((Z)-EtO2CCHCHCO2Et) | 153762-26-6

• 英文名称: Pt(2,9-dimethyl-1,10-phenanthroline)((Z)-EtO2CCHCHCO2Et)
• CAS: 153762-26-6；142198-20-7
• 化学式: C₂₂H₂₄N₂O₄Pt
• 分子量: 575.524
• InChiKey: VNLFHBBFJMMVDM-XRPAZMCKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
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• 可旋转键数：
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• 环数：
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• sp3杂化的碳原子比例：
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• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
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反应信息

• 作为反应物：
  描述：

  Pt(2,9-dimethyl-1,10-phenanthroline)((Z)-EtO2CCHCHCO2Et) 、 氯化甲基汞 以 氯仿 为溶剂， 以>80的产率得到Pt(2,9-dimethyl-1,10-phenanthroline)((Z)-EtO2CCHCHCO2Et)(HgMe)Cl
  参考文献：
  名称：

  Trigonal-bipyramidal co-ordinatively saturated platinum(II) olefin complexes bearing an organomercury fragment in axial position

  摘要：

  The reactions of organomercury halides HgR'(Cl) (R' = Me, Et, Bu(t) or Ph) with complexes of the type [Pt(dmphen){(Z)-RO2CCH = CHCO2R}] (dmphen = 2,9-dimethyl-1,10-phenanthroline; R = Me, Et or Bu(t)) have been studied. The dmphen ligand with suitable 'in-plane' steric hindrance stabilizes five-co-ordinate adducts of general formula [PtCl(HgR')(dmphen){(Z)-ROCCH-CHCO2R}] when R' = alkyl. An influence of the nature of the Hg-bound hydrocarbyl group on the reaction course is observed. Thus, a cluster containing the Pt-Hg-Pt sequence was obtained when R' = Ph or Cl. The molecular structure of [PtCl(HgMe)(dmphen){(Z)-MeO2CCH=CHCO2Me}] (space group P2(1)/c; a = 13.079(2), b =1 3.167(2), c = 15.495(3) angstrom and beta = 94.18(2)-degrees] reveals a large trans influence of the organomercury fragment.

  DOI：

  10.1039/dt9930003421
• 作为产物：
  描述：

  [Pt(2,9-dimethyl-1,10-phenanthroline)(ethene)] 、 马来酸二乙酯 以 二氯甲烷 为溶剂， 以70-80的产率得到Pt(2,9-dimethyl-1,10-phenanthroline)((Z)-EtO2CCHCHCO2Et)
  参考文献：
  名称：

  Trigonal-bipyramidal co-ordinatively saturated platinum(II) olefin complexes bearing an organomercury fragment in axial position

  摘要：

  The reactions of organomercury halides HgR'(Cl) (R' = Me, Et, Bu(t) or Ph) with complexes of the type [Pt(dmphen){(Z)-RO2CCH = CHCO2R}] (dmphen = 2,9-dimethyl-1,10-phenanthroline; R = Me, Et or Bu(t)) have been studied. The dmphen ligand with suitable 'in-plane' steric hindrance stabilizes five-co-ordinate adducts of general formula [PtCl(HgR')(dmphen){(Z)-ROCCH-CHCO2R}] when R' = alkyl. An influence of the nature of the Hg-bound hydrocarbyl group on the reaction course is observed. Thus, a cluster containing the Pt-Hg-Pt sequence was obtained when R' = Ph or Cl. The molecular structure of [PtCl(HgMe)(dmphen){(Z)-MeO2CCH=CHCO2Me}] (space group P2(1)/c; a = 13.079(2), b =1 3.167(2), c = 15.495(3) angstrom and beta = 94.18(2)-degrees] reveals a large trans influence of the organomercury fragment.

  DOI：

  10.1039/dt9930003421

文献信息

• Electrophilic Attack of [I(py)2]+(NO3−) on Three-Coordinate Pt0 Precursors: Synthesis and In Vitro Antitumor Activity of Water-Soluble, Five-Coordinate PtII Complexes
  作者：Mario Bigioni、Paolo Ganis、Achille Panunzi、Francesco Ruffo、Carmela Salvatore、Antonio Vito

  DOI：10.1002/1099-0682(200008)2000:8<1717::aid-ejic1717>3.0.co;2-1

  日期：2000.8

  [I(py)2]+(NO3−) oxidatively adds to the three-coordinate platinum(0) precursors [Pt(N,N-chelate)(olefin)] affording the cationic five-coordinate products [Pt(N,N-chelate)I(py)(olefin)]+(NO3−) (1) N,N-chelate = 2,9-Me2-1,10-phenanthroline (dmphen), 2-methyl-6-[(phenylimino)methyl]pyridine (pimpy) and 2-methyl-6-[(4-methoxyphenylimino)methyl]pyridine (mpimpy)}. The crystal structure of [Pt(pimpy)I(py)(dimethyl

  [I(py)2]+(NO3−)氧化添加到三配位铂(0)前体[Pt(N,N-螯合物)(烯烃)]，得到阳离子五配位产物[Pt(N,N) -螯合物)I(py)(烯烃)]+( -) (1) N,N-螯合物 = 2,9-Me2-1,10-菲咯啉 (dmphen), 2-methyl-6-[(phenylimino )甲基]吡啶(pimpy)和2-甲基-6-[(4-甲氧基苯基亚氨基)甲基]吡啶(mpimpy)}。报道了[Pt(pimpy)I(py)(富马酸二甲酯)]+( -)的晶体结构。晶体为三斜晶系，空间群 P1(bar)，a = 13.511(2), b = 13.754(2), c = 8.678(1) A, α = 95.2(1)°, β = 92.5(2)° , γ = 64.7(1)°, Z = 2. I 型复合物可溶于氯化溶剂和水中，测试了对包括 NSCLC H460、白血病 HL-60