| 157000-22-1

• CAS: 157000-22-1
• 化学式: C₁₄H₁₆MoO₂
• 分子量: 312.22
• InChiKey: YWIGEONKAZZRQU-IGFSWITOSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  四氧化锇 、 以 not given 为溶剂， 以68%的产率得到
  参考文献：
  名称：

  烷基锂和格氏试剂与（环戊二烯基）二羰基（2-甲基丁二烯）钼的反应：溶剂对区域选择性的影响

  摘要：

  The regioselectivity that is observed during reactions of the title complex with hydride and carbon nucleophiles was found to be solvent-dependent. In diethyl ether solution, alkyllithiums and Grignard reagents add preferentially to C-1, while in THF and other solvents C-4 addition dominates. Inclusion of complexing agents (TMEDA or HMPA) in the reactions in ether leads to a reversal of selectivity. All hydride nucleophiles add selectively at C-1, irrespective of solvent. Decomplexation of the C-1 adducts, with concomitant addition of a second nucleophile, allows the completely stereoselective construction of trisubstituted carbon-carbon double bonds. The first example of osmylation of an alkene substituent in the presence of a pi-allyl-Mo-(CO)2Cp group is described.

  DOI：

  10.1021/om00019a001
• 作为产物：
  描述：

  [(cyclopentadienyl)dicarbonyl(2-methylbutadiene)Mo](PF6) 、 乙烯基溴化镁 以 乙醚 为溶剂， 生成 、
  参考文献：
  名称：

  烷基锂和格氏试剂与（环戊二烯基）二羰基（2-甲基丁二烯）钼的反应：溶剂对区域选择性的影响

  摘要：

  The regioselectivity that is observed during reactions of the title complex with hydride and carbon nucleophiles was found to be solvent-dependent. In diethyl ether solution, alkyllithiums and Grignard reagents add preferentially to C-1, while in THF and other solvents C-4 addition dominates. Inclusion of complexing agents (TMEDA or HMPA) in the reactions in ether leads to a reversal of selectivity. All hydride nucleophiles add selectively at C-1, irrespective of solvent. Decomplexation of the C-1 adducts, with concomitant addition of a second nucleophile, allows the completely stereoselective construction of trisubstituted carbon-carbon double bonds. The first example of osmylation of an alkene substituent in the presence of a pi-allyl-Mo-(CO)2Cp group is described.

  DOI：

  10.1021/om00019a001