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    —— ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H32N4O6
    ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H29N3O5S
    ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-methyl-1,4-diazepan-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H30N4O3S
    ethyl (4S)-6-[(4-methyl-1,4-diazepan-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H30N4O5S
    ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(2-ethoxyphenyl)-2-oxo-6-[(4-prop-2-enylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H32N4O4
    ethyl (4S)-4-(2-ethoxyphenyl)-2-oxo-6-[(4-prop-2-enylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(4-methylsulfanylphenyl)-2-oxo-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H28N6O3S
    ethyl (4R)-4-(4-methylsulfanylphenyl)-2-oxo-6-[(4-pyrimidin-2-ylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(4-ethoxy-3-methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H33N3O5
    ethyl (4S)-4-(4-ethoxy-3-methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C25H29FN4O3S
    ethyl (4S)-6-[[4-(2-fluorophenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H31N3O5S
    ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-6-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C28H33N3O5
    ethyl (4R)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-6-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-methylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C20H28N4O3S
    ethyl (4R)-6-[(4-methylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H29N3O6
    ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-cyclohexylpiperazin-1-yl)methyl]-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H33FN4O3
    ethyl (4S)-6-[(4-cyclohexylpiperazin-1-yl)methyl]-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H32N4O6
    ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H33N3O7
    ethyl (4R)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H27N3O3S
    ethyl (4S)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C25H35N3O7
    ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-6-(pyrrolidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H29N3O5
    ethyl (4S)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-6-(pyrrolidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(4-methylsulfanylphenyl)-2-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C25H30N4O3S
    ethyl (4S)-4-(4-methylsulfanylphenyl)-2-oxo-6-[(4-phenylpiperazin-1-yl)methyl]-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-benzylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C27H33N3O3S
    ethyl (4R)-6-[(4-benzylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-carbamoylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H28N4O4S
    ethyl (4R)-6-[(4-carbamoylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[[4-(2,4-dimethylphenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C27H34N4O3S
    ethyl (4R)-6-[[4-(2,4-dimethylphenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H30N4O5S
    ethyl (4S)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(2-ethoxyphenyl)-2-oxo-6-(piperidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H29N3O4
    ethyl (4R)-4-(2-ethoxyphenyl)-2-oxo-6-(piperidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (3S)-1-[4-[(2,4-difluorophenyl)methyl]furo[3,2-b]pyrrole-5-carbonyl]piperidine-3-carboxylate —— C22H22F2N2O4
    ethyl (3S)-1-[4-[(2,4-difluorophenyl)methyl]furo[3,2-b]pyrrole-5-carbonyl]piperidine-3-carboxylate
    —— ethyl (4S)-4-(2-chlorophenyl)-6-[(4-cyclohexylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H33ClN4O3
    ethyl (4S)-4-(2-chlorophenyl)-6-[(4-cyclohexylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H31N3O6
    ethyl (4S)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-4-(2,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H33N3O6
    ethyl (4R)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-4-(2,4,5-trimethoxyphenyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H27N3O3S
    ethyl (4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(3-methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H29N3O4
    ethyl (4S)-4-(3-methoxyphenyl)-6-[(4-methylpiperidin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H32N4O5
    ethyl (4R)-6-[(4-ethoxycarbonylpiperazin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H30N4O5
    ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(2-ethoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H31N3O5S
    ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(4-methylsulfanylphenyl)-6-(morpholin-4-ylmethyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C19H25N3O4S
    ethyl (4S)-4-(4-methylsulfanylphenyl)-6-(morpholin-4-ylmethyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[[4-(2,3-dimethylphenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C27H34N4O3S
    ethyl (4S)-6-[[4-(2,3-dimethylphenyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H30N4O4
    ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(4-ethylphenyl)-6-[(4-methylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H30N4O3
    ethyl (4R)-4-(4-ethylphenyl)-6-[(4-methylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(azepan-1-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H29N3O4
    ethyl (4R)-6-(azepan-1-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H29N3O6
    ethyl (4S)-6-(1,4-dioxa-8-azaspiro[4.5]decan-8-ylmethyl)-4-(3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H28N4O4S
    ethyl (4R)-6-[(4-acetylpiperazin-1-yl)methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(2-ethoxyphenyl)-6-[(4-methylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C21H30N4O4
    ethyl (4R)-4-(2-ethoxyphenyl)-6-[(4-methylpiperazin-1-yl)methyl]-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C26H31N3O5
    ethyl (4R)-6-(3,4-dihydro-1H-isoquinolin-2-ylmethyl)-4-(4-ethoxy-3-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(3-fluorophenyl)-1-[2-(2-methoxyethylamino)-2-oxoethyl]-6-methyl-2-oxo-3,4-dihydropyridine-5-carboxylate —— C20H25FN2O5
    ethyl (4S)-4-(3-fluorophenyl)-1-[2-(2-methoxyethylamino)-2-oxoethyl]-6-methyl-2-oxo-3,4-dihydropyridine-5-carboxylate
    —— ethyl (4S)-6-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H28N4O5S
    ethyl (4S)-6-[[4-(furan-2-carbonyl)piperazin-1-yl]methyl]-4-(4-methylsulfanylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-(azepan-1-ylmethyl)-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C20H26FN3O3
    ethyl (4R)-6-(azepan-1-ylmethyl)-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C22H28FN3O5
    ethyl (4R)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(3-fluorophenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-4-(4-methylsulfanylphenyl)-2-oxo-6-(pyrrolidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C19H25N3O3S
    ethyl (4S)-4-(4-methylsulfanylphenyl)-2-oxo-6-(pyrrolidin-1-ylmethyl)-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4R)-4-(3-methoxyphenyl)-6-(morpholin-4-ylmethyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C19H25N3O5
    ethyl (4R)-4-(3-methoxyphenyl)-6-(morpholin-4-ylmethyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C24H33N3O5
    ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(4-ethylphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate
    —— ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(2-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate —— C23H31N3O6
    ethyl (4S)-6-[(4-ethoxycarbonylpiperidin-1-yl)methyl]-4-(2-methoxyphenyl)-2-oxo-3,4-dihydro-1H-pyrimidine-5-carboxylate