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    —— Ethyl 2-[4-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-2,3-dioxo-5-phenylpyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C26H22N4O5S
    Ethyl 2-[4-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-2,3-dioxo-5-phenylpyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Ethyl 2-[2-(4-tert-butylphenyl)-3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C30H30N4O5S
    Ethyl 2-[2-(4-tert-butylphenyl)-3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Ethyl 2-[3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-2-(3-hydroxyphenyl)-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C26H22N4O6S
    Ethyl 2-[3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-2-(3-hydroxyphenyl)-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— Ethyl 2-[2-(3,4-dimethoxyphenyl)-3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate —— C28H26N4O7S
    Ethyl 2-[2-(3,4-dimethoxyphenyl)-3-[hydroxy-(2-methylimidazo[1,2-a]pyridin-3-yl)methylidene]-4,5-dioxopyrrolidin-1-yl]-4-methyl-1,3-thiazole-5-carboxylate
    —— ethyl 1-[4-[[(2R)-3-methylbutan-2-yl]carbamoylamino]phenyl]pyrazole-3-carboxylate —— C18H24N4O3
    ethyl 1-[4-[[(2R)-3-methylbutan-2-yl]carbamoylamino]phenyl]pyrazole-3-carboxylate
    —— ethyl 1-[4-[[(2R)-2-(dimethylamino)-2-(furan-2-yl)ethyl]carbamoylamino]phenyl]pyrazole-3-carboxylate —— C21H25N5O4
    ethyl 1-[4-[[(2R)-2-(dimethylamino)-2-(furan-2-yl)ethyl]carbamoylamino]phenyl]pyrazole-3-carboxylate
    —— ethyl 4-[(2S)-2-hydroxy-3-[4-(2-methylfuran-3-carbonyl)piperazin-1-yl]propoxy]benzoate —— C22H28N2O6
    ethyl 4-[(2S)-2-hydroxy-3-[4-(2-methylfuran-3-carbonyl)piperazin-1-yl]propoxy]benzoate
    —— (E)-N-[2-(pyrazin-2-ylamino)ethyl]-3-[4-(pyridin-3-ylmethoxy)phenyl]prop-2-enamide —— C21H21N5O2
    (E)-N-[2-(pyrazin-2-ylamino)ethyl]-3-[4-(pyridin-3-ylmethoxy)phenyl]prop-2-enamide
    —— (E)-3-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]-N-[2-(pyrazin-2-ylamino)ethyl]prop-2-enamide —— C20H21N5O2S
    (E)-3-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]-N-[2-(pyrazin-2-ylamino)ethyl]prop-2-enamide
    —— ethyl N-[(3S)-1-(pyridin-4-ylcarbamoyl)piperidin-3-yl]carbamate —— C14H20N4O3
    ethyl N-[(3S)-1-(pyridin-4-ylcarbamoyl)piperidin-3-yl]carbamate
    —— Ethyl 1-[1-butyl-5-cyano-4-methyl-6-oxo-3-[(4-oxo-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]pyridin-2-yl]piperidine-3-carboxylate —— C26H32N4O4S2
    Ethyl 1-[1-butyl-5-cyano-4-methyl-6-oxo-3-[(4-oxo-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]pyridin-2-yl]piperidine-3-carboxylate
    —— (E)-3-[5-bromo-2-(difluoromethoxy)phenyl]-N-[2-(pyrazin-2-ylamino)ethyl]prop-2-enamide —— C16H15BrF2N4O2
    (E)-3-[5-bromo-2-(difluoromethoxy)phenyl]-N-[2-(pyrazin-2-ylamino)ethyl]prop-2-enamide
    —— (E)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]-3-thiophen-2-ylprop-2-enamide —— C21H25N3OS
    (E)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]-3-thiophen-2-ylprop-2-enamide
    —— (E)-3-(4-cyanophenyl)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]prop-2-enamide —— C24H26N4O
    (E)-3-(4-cyanophenyl)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]prop-2-enamide
    —— ethyl 6-[4-[[(1S)-1-(2,4-dimethyl-1,3-thiazol-5-yl)ethyl]carbamoyl]piperazin-1-yl]pyridine-3-carboxylate —— C20H27N5O3S
    ethyl 6-[4-[[(1S)-1-(2,4-dimethyl-1,3-thiazol-5-yl)ethyl]carbamoyl]piperazin-1-yl]pyridine-3-carboxylate
    —— (E)-3-(1,3-benzoxazol-2-yl)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]prop-2-enamide —— C24H26N4O2
    (E)-3-(1,3-benzoxazol-2-yl)-N-[3-[4-(cyclopropylmethyl)piperazin-1-yl]phenyl]prop-2-enamide
    —— Ethyl 1-[1-butyl-5-cyano-4-methyl-6-oxo-3-[(4-oxo-3-pentyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]pyridin-2-yl]piperidine-3-carboxylate —— C28H38N4O4S2
    Ethyl 1-[1-butyl-5-cyano-4-methyl-6-oxo-3-[(4-oxo-3-pentyl-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]pyridin-2-yl]piperidine-3-carboxylate
    —— Ethyl 1-[(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methylsulfonyl]piperidine-4-carboxylate —— C18H29NO5S
    Ethyl 1-[(7,7-dimethyl-2-oxo-1-bicyclo[2.2.1]heptanyl)methylsulfonyl]piperidine-4-carboxylate
    —— Ethyl 4-[[5-(dibenzylsulfamoyl)pyridin-2-yl]amino]benzoate —— C28H27N3O4S
    Ethyl 4-[[5-(dibenzylsulfamoyl)pyridin-2-yl]amino]benzoate
    —— (E)-3-(5-bromofuran-2-yl)-N-(5-cyano-2-ethoxyphenyl)prop-2-enamide —— C16H13BrN2O3
    (E)-3-(5-bromofuran-2-yl)-N-(5-cyano-2-ethoxyphenyl)prop-2-enamide
    —— ethyl N-[(2R)-1-[[(2R)-2-methoxy-2-phenylethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate —— C17H26N2O4
    ethyl N-[(2R)-1-[[(2R)-2-methoxy-2-phenylethyl]amino]-3-methyl-1-oxobutan-2-yl]carbamate
    —— (E)-3-[4-(dimethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide —— C20H24N2O4S
    (E)-3-[4-(dimethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-3-(1,3-benzodioxol-5-yl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one —— C20H23N3O3S
    (E)-3-(1,3-benzodioxol-5-yl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one
    —— (E)-3-[4-(cyclopropylsulfamoyl)phenyl]-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide —— C21H24N2O4S
    (E)-3-[4-(cyclopropylsulfamoyl)phenyl]-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]-3-phenylbut-2-en-1-one —— C20H25N3OS
    (E)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]-3-phenylbut-2-en-1-one
    —— Ethyl 4-[[5-[ethyl(phenyl)sulfamoyl]pyridin-2-yl]amino]benzoate —— C22H23N3O4S
    Ethyl 4-[[5-[ethyl(phenyl)sulfamoyl]pyridin-2-yl]amino]benzoate
    —— (E)-3-(3,4-dimethoxyphenyl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one —— C21H27N3O3S
    (E)-3-(3,4-dimethoxyphenyl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one
    —— (E)-3-[4-(diethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide —— C22H28N2O4S
    (E)-3-[4-(diethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-3-(3-cyanophenyl)-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide —— C19H18N2O2
    (E)-3-(3-cyanophenyl)-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-3-(5-chloro-1,3-dimethylpyrazol-4-yl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one —— C18H24ClN5OS
    (E)-3-(5-chloro-1,3-dimethylpyrazol-4-yl)-1-[4-[(2-ethyl-1,3-thiazol-4-yl)methyl]piperazin-1-yl]prop-2-en-1-one
    —— (E)-N-[(2S)-2-methoxy-2-phenylethyl]-3-[4-(methylsulfamoyl)phenyl]prop-2-enamide —— C19H22N2O4S
    (E)-N-[(2S)-2-methoxy-2-phenylethyl]-3-[4-(methylsulfamoyl)phenyl]prop-2-enamide
    —— (E)-3-[4-(ethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide —— C20H24N2O4S
    (E)-3-[4-(ethylsulfamoyl)phenyl]-N-[(2S)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-N-(5-cyano-2-ethoxyphenyl)-3-(6-nitro-1,3-benzodioxol-5-yl)prop-2-enamide —— C19H15N3O6
    (E)-N-(5-cyano-2-ethoxyphenyl)-3-(6-nitro-1,3-benzodioxol-5-yl)prop-2-enamide
    —— (E)-N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-3-(1,3-thiazol-2-yl)prop-2-enamide —— C17H22N6OS
    (E)-N-[3-(4-pyrimidin-2-ylpiperazin-1-yl)propyl]-3-(1,3-thiazol-2-yl)prop-2-enamide
    —— Ethyl 4-[[5-(4-methylpiperazin-1-yl)sulfonylpyridin-2-yl]amino]benzoate —— C19H24N4O4S
    Ethyl 4-[[5-(4-methylpiperazin-1-yl)sulfonylpyridin-2-yl]amino]benzoate
    —— (E)-3-(2,6-difluorophenyl)-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide —— C18H17F2NO2
    (E)-3-(2,6-difluorophenyl)-N-[(2R)-2-methoxy-2-phenylethyl]prop-2-enamide
    —— (E)-3-(2,5-dimethoxyphenyl)-N-[[4-(4-methoxyphenyl)oxan-4-yl]methyl]prop-2-enamide —— C24H29NO5
    (E)-3-(2,5-dimethoxyphenyl)-N-[[4-(4-methoxyphenyl)oxan-4-yl]methyl]prop-2-enamide
    —— ethyl N-[3-[[4-(4-methoxyphenyl)oxan-4-yl]methylamino]-3-oxopropyl]carbamate —— C19H28N2O5
    ethyl N-[3-[[4-(4-methoxyphenyl)oxan-4-yl]methylamino]-3-oxopropyl]carbamate
    —— Ethyl 4-[(5-morpholin-4-ylsulfonylpyridin-2-yl)amino]benzoate —— C18H21N3O5S
    Ethyl 4-[(5-morpholin-4-ylsulfonylpyridin-2-yl)amino]benzoate
    —— (E)-N-(2-amino-2-oxoethyl)-N-cyclopentyl-3-(2-fluorophenyl)but-2-enamide —— C17H21FN2O2
    (E)-N-(2-amino-2-oxoethyl)-N-cyclopentyl-3-(2-fluorophenyl)but-2-enamide
    —— Ethyl 4-[(5-pyrrolidin-1-ylsulfonylpyridin-2-yl)amino]benzoate —— C18H21N3O4S
    Ethyl 4-[(5-pyrrolidin-1-ylsulfonylpyridin-2-yl)amino]benzoate
    —— (E)-3-(2-fluorophenyl)-N-[4-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]but-2-enamide —— C18H20FN3O2S
    (E)-3-(2-fluorophenyl)-N-[4-(morpholin-4-ylmethyl)-1,3-thiazol-2-yl]but-2-enamide
    —— (E)-N-[(2S)-2-cyanopropyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-ethylprop-2-enamide —— C17H20N2O3
    (E)-N-[(2S)-2-cyanopropyl]-3-(2,3-dihydro-1,4-benzodioxin-6-yl)-N-ethylprop-2-enamide
    —— (E)-3-pyridin-2-yl-1-[(2R)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)pyrrolidin-1-yl]prop-2-en-1-one —— C19H23N5O
    (E)-3-pyridin-2-yl-1-[(2R)-2-(6,7,8,9-tetrahydro-5H-[1,2,4]triazolo[4,3-a]azepin-3-yl)pyrrolidin-1-yl]prop-2-en-1-one
    —— ethyl 4-[(Z)-3-[[(2R)-2-cyanopropyl]-ethylamino]-3-oxoprop-1-enyl]-1-ethyl-2,5-dimethylpyrrole-3-carboxylate —— C20H29N3O3
    ethyl 4-[(Z)-3-[[(2R)-2-cyanopropyl]-ethylamino]-3-oxoprop-1-enyl]-1-ethyl-2,5-dimethylpyrrole-3-carboxylate
    —— (E)-3-(1-butyl-5-chloro-3-methylpyrazol-4-yl)-N-(3-methylsulfonylpropyl)prop-2-enamide —— C15H24ClN3O3S
    (E)-3-(1-butyl-5-chloro-3-methylpyrazol-4-yl)-N-(3-methylsulfonylpropyl)prop-2-enamide
    —— (E)-N-(3-methylsulfonylpropyl)-3-[4-(pyridin-3-ylmethoxy)phenyl]prop-2-enamide —— C19H22N2O4S
    (E)-N-(3-methylsulfonylpropyl)-3-[4-(pyridin-3-ylmethoxy)phenyl]prop-2-enamide
    —— (E)-N-[(2S)-2-cyanopropyl]-3-[4-(cyclopropylsulfamoyl)phenyl]-N-ethylprop-2-enamide —— C18H23N3O3S
    (E)-N-[(2S)-2-cyanopropyl]-3-[4-(cyclopropylsulfamoyl)phenyl]-N-ethylprop-2-enamide
    —— ethyl N-[(2S)-1-[[2-(3-carbamoylphenoxy)acetyl]amino]-4-methylpentan-2-yl]carbamate —— C18H27N3O5
    ethyl N-[(2S)-1-[[2-(3-carbamoylphenoxy)acetyl]amino]-4-methylpentan-2-yl]carbamate
    —— (E)-3-(2-fluorophenyl)-N-[[6-(2-methylimidazol-1-yl)pyridin-3-yl]methyl]but-2-enamide —— C20H19FN4O
    (E)-3-(2-fluorophenyl)-N-[[6-(2-methylimidazol-1-yl)pyridin-3-yl]methyl]but-2-enamide