蒽环类药物
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | [2-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] 4-oxopentanoate | —— | C32H35NO13 |
| —— | octadec-9-enyl N-[4-hydroxy-4-[[3-hydroxy-2-methyl-6-[[3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]butyl]carbamate | —— | C50H72N2O14 |
| —— | (7S)-9-acetyl-6,9,11-trihydroxy-7-[5-hydroxy-6-methyl-4-[(2-nitrophenyl)methylamino]oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | —— | C34H35ClN2O12 |
| —— | 2-amino-2-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]acetaldehyde | —— | C27H30N2O10 |
| —— | (7S,9S)-6,9,11-trihydroxy-9-[(E)-C-(hydroxymethyl)-N-[[[4-[(2-hydroxypropylamino)methyl]-2,2,4-trimethylhexanoyl]-phosphanylidene-lambda4-sulfanyl]amino]carbonimidoyl]-7-(5-hydroxy-6-methyloxan-2-yl)oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C40H56N3O12PS |
| —— | 9-acetyl-7-(5-fluoro-4,6-dimethyloxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;7-(5,5-difluoro-4-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;7-(5-fluoro-4,6-dimethyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;7-(5-fluoro-4-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C138H140F6O51 |
| —— | 6-N'-acetyl-1-N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hexanedihydrazide | —— | C35H43N5O13 |
| —— | 2-acetamido-N-[(3S,4R,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]butanamide | —— | C33H38N2O13 |
| —— | N-[2-[2-[2-[2-[2-[2-[3-[2-[1-[(2R,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hydrazinyl]-3-oxopropoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl]-6-oxo-5-(phenylhydrazinylidene)naphthalene-2-sulfonamide | —— | C58H70N6O20S |
| —— | 6-(2,5-dioxocyclopent-3-en-1-yl)-N-[3-hydroxy-2-[(2R,4S)-2,5,12-trihydroxy-4-(5-hydroxy-4,6-dimethyloxan-2-yl)oxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]prop-1-enyl]hexanamide | —— | C40H45NO13 |
| —— | N'-[2-oxo-1-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethyl]-3-(pyridin-2-yldisulfanyl)propanehydrazide | —— | C40H44N4O13S2 |
| —— | (8R,10S)-10-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6-ethoxy-11-hydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione;N-[(2S,3S,4S,6S)-6-[[(1S,3R)-3-[2-(1,1-diphenylpropoxy)acetyl]-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-1-yl]oxy]-2,3-dimethyloxan-4-yl]-2,2,2-trifluoroacetamide | —— | C74H77F3N2O20 |
| —— | N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-3-(2,5-dioxopyrrol-1-yl)propanehydrazide | —— | C34H36N4O13 |
| —— | (3Z)-N-[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-3-propanoyl-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]-3-methoxyiminobutanamide | —— | C33H38N2O12 |
| —— | 2-[1-[4-[3-[2-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hydrazinyl]-3-oxopropyl]phenyl]-2,5-dihydroxypyrrol-3-yl]sulfanyl-N-methylacetamide | —— | C43H47N5O14S |
| —— | N'-[1-[(4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-7-formyl-2,5,12-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-6-(2,5-dioxopyrrol-1-yl)hexanehydrazide | —— | C37H40N4O13 |
| —— | (2,5-dihydroxypyrrol-1-yl) 5-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-5-oxopentanoate | —— | C36H38N2O16 |
| —— | 1-[(2S,3R)-3-hydroxy-2-methyl-6-[[(2S,3R)-2,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-1-yl]oxy]oxan-4-yl]-3-[2-[2-[2-(methylcarbamoylamino)ethoxy]ethoxy]ethyl]urea | —— | C36H46N4O15 |
| —— | methyl (2R)-2-ethyl-2,5,7,10-tetrahydroxy-4-[4-hydroxy-5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate | —— | C40H48O17 |
| —— | N'-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]benzenesulfonohydrazide | —— | C33H35N3O12S |
| —— | 1-[(2S,3R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]-3-[2-[2-[2-(methylcarbamoylamino)ethoxy]ethoxy]ethyl]urea | —— | C36H46N4O15 |
| —— | 6,11-Dihydroxy-8-(2-hydroxyacetyl)-10-[5-hydroxy-6-methyl-4-(propylamino)oxan-2-yl]oxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione | —— | C30H35NO10 |
| —— | 3-[3-[(2R)-2-amino-3-[[(2R)-6-amino-1-[[(2R)-6-amino-1-[[(2R)-1-[[(2R)-6-amino-1-(methylamino)-1-oxohexan-2-yl]amino]-3-(1H-indol-3-yl)-1-oxopropan-2-yl]amino]-1-oxohexan-2-yl]amino]-1-oxohexan-2-yl]amino]-3-oxopropyl]sulfanyl-2,5-dihydroxypyrrol-1-yl]-N-[(2S,3S,4S)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]benzamide | —— | C71H90N12O19S |
| —— | 2-[2-[[3-hydroxy-2-methyl-6-[[(1R)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyloxy]ethyldisulfanyl]ethyl N-[2-[(carbamothioylhydrazinylidene)methyl]pyridin-3-yl]carbamate | —— | C40H44N6O15S3 |
| —— | methyl (2R)-4-[5-[5-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-4-hydroxy-6-methyloxan-2-yl]oxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate | —— | C42H55NO17 |
| —— | (7S,9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-[(E)-C-(hydroxymethyl)-N-[[[4-[(2-hydroxypropylamino)methyl]-2,2,4-trimethylhexanoyl]-phosphanylidene-lambda4-sulfanyl]amino]carbonimidoyl]-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C40H57N4O12PS |
| —— | (7S,9S)-7-(4-amino-6-methyl-5-phenylmethoxyoxan-2-yl)oxy-6,9,11-trihydroxy-9-propanoyl-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | —— | C34H36ClNO9 |
| —— | Pirarubicin HCl | 95343-20-7 | C32H38ClNO12 |
| —— | (7S,9S)-7-[(2S,4R,5R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;iron(3+) | —— | C27H29FeNO11+3 |
| —— | (7S,9R,10R)-9-acetyl-7-[(2R,3R,4R,5S,6S)-4-amino-3-fluoro-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,10,11-tetrahydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C27H28FNO11 |
| —— | (7S,9S)-7-[(2R,3R,4R,5S,6S)-4-amino-3-fluoro-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C27H28FNO11 |
| —— | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-9-[N-(cyclohexylideneamino)-C-methylcarbonimidoyl]-4,6,9-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C32H37N3O8 |
| —— | benzyl N-[(2S)-1-[[6-amino-1-[4-[[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyloxymethyl]anilino]-1-oxohexan-2-yl]amino]-3-methyl-1-oxobutan-2-yl]carbamate | —— | C54H63N5O17 |
| —— | N'-[3-hydroxy-2-methyl-6-[(3,5,12-trihydroxy-10-methoxy-6,11-dioxo-3-propanoyl-2,4-dihydro-1H-tetracen-1-yl)oxy]oxan-4-yl]-N,N-dimethylmethanimidamide | —— | C31H36N2O10 |
| —— | N'-[6-[[3-[N-(cyclohexylideneamino)-C-methylcarbonimidoyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-N,N-dimethylmethanimidamide | —— | C36H44N4O9 |
| —— | (7S,9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-[(Z)-C-(hydroxymethyl)-N-(methylamino)carbonimidoyl]-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | —— | C28H33N3O10 |
| —— | tert-butyl N-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]carbamate | —— | C31H37N3O11 |
| —— | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-9-(1-nitrosoethyl)-8,10-dihydro-7H-tetracene-5,12-dione | —— | C27H30N2O10 |
| —— | (8R,10S)-10-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,11-dihydroxy-1-methoxy-8-propanoyl-7,8,9,10-tetrahydrotetracene-5,12-dione;(8R,10S)-6,11-dihydroxy-8-(2-hydroxyacetyl)-10-[(2R,4S,5R,6S)-5-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione | —— | C56H62N2O19 |
| —— | N-[(Z)-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-4-oxopentanamide | —— | C32H37N3O12 |
| —— | (7S,9S)-9-acetyl-7-[(2S,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | 60660-72-2 | C26H28ClNO9 |
| —— | N-[6-[[(1S,3S)-3-[(Z)-C-ethyl-N-methoxycarbonimidoyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-5-oxohexanamide | —— | C35H42N2O12 |
| —— | [2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] 1-hydroxy-2,2,6,6-tetramethylpiperidine-4-carboxylate | —— | C37H46N2O13 |
| —— | (3S,6S,9S,12S,20S)-12-[[2-[[1-[(2R,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-5,12-dihydroxy-7-methoxy-2-methyl-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]oxyacetyl]amino]-6-[3-(diaminomethylideneamino)propyl]-3-(hydroxymethyl)-9-(2-methylpropyl)-2,5,8,11,14-pentaoxo-1,4,7,10,15-pentazacycloicosane-20-carboxylic acid | —— | C55H77N11O19 |
| —— | (7S,9S)-9-acetyl-6,9,11-trihydroxy-7-[5-hydroxy-6-methyl-4-[(3-nitrophenyl)methylamino]oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | —— | C34H35ClN2O12 |
| —— | 2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-(2-methylhydrazinyl)acetaldehyde | —— | C28H33N3O10 |
| —— | (2S)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-5-[[3-[[3-[2-[(2R)-2-[(4R,6S)-6-[(4R,6R)-4-(dimethylamino)-6-[[(1S,3R,4R)-3-ethyl-3,10,12-trihydroxy-4-methoxycarbonyl-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2-methyloxan-3-yl]oxy-4-hydroxy-2-methyloxan-3-yl]oxy-6-methyl-3,4-dihydro-2H-pyran-5-yl]hydrazinyl]-3-oxopropyl]disulfanyl]-1-hydroperoxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid | —— | C67H81N11O23S2 |
| —— | 4-Methylbenzyl-N-bis[daunomycin] | —— | C62H66N2O20+2 |
| —— | 2-[[6-[2-(5,12-dihydroxy-7-methoxy-2-methyl-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl)-2-oxoethoxy]oxan-2-yl]methoxy]-N-[2-(2,5-dioxopyrrol-1-yl)ethyl]acetamide | —— | C36H38N2O12 |
| —— | [2-[[(3R,4S,5S,6R,7R,9R,10S,11S,12R,13S,14R)-4-[5-[4-[[(5S,5aS,6aS,7S,10aS)-9-carbamoyl-7-(dimethylamino)-1,5,10a-trihydroxy-5-methyl-8,10,11,12-tetraoxo-6,6a,7,11a-tetrahydro-5aH-tetracen-2-yl]carbamoylamino]butylcarbamoyloxy]-4-methoxy-4,6-dimethyloxan-2-yl]oxy-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyl-10-[(2-methylpropan-2-yl)oxycarbonylamino]-2-oxo-oxacyclotetradec-6-yl]oxy]-4-(dimethylamino)-6-methyloxan-3-yl] acetate | —— | C72H113N7O25 |
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