蒽环类药物
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-9-(2-氯乙酰基)-4,6,9,11-四羟基-8,10-二氢-7H-并四苯-5,12-二酮 | 14-Chlorocarubicin | 126722-64-3 | C26H26ClNO10 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-6,9-二羟基-9-(2-羟基乙酰基)-8,10-二氢-7H-并四苯-5,12-二酮 | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9-dihydroxy-9-(2-hydroxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione | 77312-69-7 | C26H27NO9 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-6,9,11-三羟基-9-戊酰-8,10-二氢-7H-并四苯-5,12-二酮盐酸盐 | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-pentanoyl-8,10-dihydro-7H-tetracene-5,12-dione;hydron;chloride | —— | C29H34ClNO9 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-6,9,11-三羟基-9-壬酰-8,10-二氢-7H-并四苯-5,12-二酮盐酸盐 | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-nonanoyl-8,10-dihydro-7H-tetracene-5,12-dione;hydron;chloride | —— | C33H42ClNO9 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-6,9,11-三羟基-9-(2-甲基丙酰基)-8,10-二氢-7H-并四苯-5,12-二酮盐酸盐 | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-methylpropanoyl)-8,10-dihydro-7H-tetracene-5,12-dione;hydron;chloride | —— | C28H32ClNO9 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-6,9,11-三羟基-4-甲氧基-9-(2-氧代丙基)-8,10-二氢-7H-并四苯-5,12-二酮 | Feudomycin B | 79438-97-4 | C28H31NO10 |
| 7-(4-氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-1,6,9,11-四羟基-9-(1-羟基乙基)-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮 | 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-1,6,9,11-tetrahydroxy-9-(1-hydroxyethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | 74273-36-2 | C27H31NO11 |
| 7-(4-氨基-5-碘-6-甲基四氢吡喃-2-基)氧基-9-(1,2-二羟基乙基)-6,9,11-三羟基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮 | 4'-Deoxy-4'-iododoxorubicinol | 111865-30-6 | C27H30INO10 |
| 7-(4-二甲基氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-9-乙基-9,10,11-三羟基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮 | 4-O-Methylyellamycin A | 146565-63-1 | C29H35NO9 |
| 7-(4-二甲基氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基-9-乙基-6,9,10,11-四羟基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮 | 4-O-Methylbetaclamycin T | 127676-54-4 | C29H35NO10 |
| 7-(4,5-二羟基-3-碘-6-甲基四氢吡喃-2-基)氧基-6,9,11-三羟基-9-(羟基甲基)-8,10-二氢-7H-并四苯-5,12-二酮 | Moflomycin | 107430-03-5 | C25H25IO10 |
| 7-(4,5-二羟基-3-甲氧基-6-甲基四氢吡喃-2-基)氧基-2,4,6,9-四羟基-8-甲氧基-9-甲基-8,10-二氢-7H-并四苯-5,12-二酮 | 2-Demethylsteffimycin D | 132354-18-8 | C27H30O12 |
| 7,8,9,10-四氢-6,8,11-三羟基-8-(1-羟基乙基)-1-甲氧基-10-((2,3,6-三脱氧-3-(甲酰氨基)-alpha-L-来苏-己糖吡喃糖苷)氧基)-5,12-并四苯醌 | Baumycin C2 | 64479-55-6 | C28H31NO11 |
| 7,10-二[(4-二甲基氨基-5-羟基-6-甲基四氢吡喃-2-基)氧基]-9-乙基-4,9,11-三羟基-8,10-二氢-7H-并四苯-5,12-二酮 | Yellamycin B | 119445-99-7 | C36H48N2O11 |
| 7(O)-(3-氨基-2,3,6-三脱氧-2-氟塔罗吡喃糖基)阿霉酮盐酸盐 | (7S,9S)-7-[(2R,3R,4R,5S,6S)-4-amino-3-fluoro-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydron;chloride | —— | C27H29ClFNO11 |
| 6-(2-甲氧基乙氧基)-2,5,8,11-四氧杂十二烷 | Auramycin C | 83753-71-3 | C35H43NO13 |
| 6,9,11-三羟基-9-(1-羟基乙基)-7-[(4S,5S,6S)-5-羟基-6-甲基-4-吗啉-4-基四氢吡喃-2-基]氧基-4-甲氧基-8,10-二氢-7H-并四苯-5,12-二酮 | 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(1-hydroxyethyl)-1-methoxy-10-((2,3,6-trideoxy-3-(4-morpholinyl)-alpha-L-lyxo-hexopyranosyl)oxy)- | 79867-79-1 | C31H37NO11 |
| 5-溴-3-碘-1-(p-甲苯磺酰)吡咯并[2,3-b]吡啶 | [6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-3,4-bis[(4-nitrobenzoyl)oxy]oxan-2-yl]methyl 4-nitrobenzoate | 98103-10-7 | C48H37N3O21 |
| 5-氨基-1,2-二氢-1-(2,4,6-三氯苯基)-3H-吡唑-3-酮 | (8S-cis)-8-Acetyl-10-((6-deoxy-2-O-methyl-alpha-L-talopyranosyl)oxy)-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxy-5,12-naphthacenedione | 124209-61-6 | C28H30O12 |
| 4H-环戊-1,3-二噁唑-6-醇,3a,6a-二氢-2,2,6a-三甲基-,6-乙酸酯,(3aR,6aR)- | Auramycin G | 83753-73-5 | C41H53NO14 |
| 4-庚基苯基4-反-(4-庚基环己基)苯酸酯 | Auramycin F | 83829-32-7 | C41H53NO15 |
| 4-去甲氧基-10,10-二甲基柔红霉素 | 4-Demethoxy-10,10-dimethyldaunomycin | 91003-74-6 | C28H31NO9 |
| 4-[5-[5-(5-氨基-6-甲基四氢吡喃-2-基)氧基-4-羟基-6-甲基四氢吡喃-2-基]氧基-4-二甲基氨基-6-甲基四氢吡喃-2-基]氧基-2-乙基-2,5,7-三羟基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 4'''-(R)-Aminoaclacinomycin A | 76439-76-4 | C42H56N2O14 |
| 4-[5-[5-(5-乙酰氨基-6-甲基四氢吡喃-2-基)氧基-4-羟基-6-甲基四氢吡喃-2-基]氧基-4-二甲基氨基-6-甲基四氢吡喃-2-基]氧基-2-乙基-2,5,7-三羟基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 4'''-Aclacinomycinamide | 79391-09-6 | C44H58N2O15 |
| 4-[5-(4,5-二羟基-6-甲基四氢吡喃-2-基)氧基-4-羟基-6-甲基四氢吡喃-2-基]氧基-2-乙基-2,5,7-三羟基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | Antibiotic MA 144U9 | 79638-26-9 | C34H40O14 |
| 4-[4-二甲基氨基-6-甲基-5-[6-甲基-5-[(6-甲基-5-氧代-2H-吡喃-2-基)氧基]四氢吡喃-2-基]氧基四氢吡喃-2-基]氧基-2-乙基-2,5,7,10-四羟基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | methyl 4-[4-(dimethylamino)-6-methyl-5-[6-methyl-5-[(6-methyl-5-oxo-2H-pyran-2-yl)oxy]oxan-2-yl]oxyoxan-2-yl]oxy-2-ethyl-2,5,7,10-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate | 147657-35-0 | C42H51NO15 |
| 4-[4-二甲基氨基-6-甲基-5-[6-甲基-5-(6-甲基-5-氧代四氢吡喃-2-基)氧基四氢吡喃-2-基]氧基四氢吡喃-2-基]氧基-2-乙基-2,5,7,12-四羟基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | Epelmycin A | 107807-25-0 | C42H53NO15 |
| 4-[4-二甲基氨基-5-[4-羟基-6-甲基-5-(6-甲基-5-氧代四氢吡喃-2-基)氧基四氢吡喃-2-基]氧基-6-甲基四氢吡喃-2-基]氧基-2-乙基-2,7-二羟基-5-甲氧基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 6-O-Methylaclacinomycin | 76264-92-1 | C43H55NO15 |
| 4-[4-二甲基氨基-5-[4-羟基-6-甲基-5-(6-甲基-5-氧代四氢吡喃-2-基)氧基四氢吡喃-2-基]氧基-6-甲基四氢吡喃-2-基]氧基-2-乙基-2,5-二羟基-7-甲氧基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 4-O-Methylaclacinomycin | 76304-86-4 | C43H55NO15 |
| 4-[4-二甲基氨基-5-[4-羟基-6-甲基-5-(6-甲基-5-氧代四氢吡喃-2-基)氧基四氢吡喃-2-基]氧基-6-甲基四氢吡喃-2-基]氧基-2,5,7,10-四羟基-6,11-二氧代-2-(2-氧代丙基)-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 1-Hydroxysulfurmycin A | 79234-80-3 | C43H53NO17 |
| 4-[4-二甲基氨基-5-[4-羟基-6-甲基-5-(6-甲基-5-氧代四氢吡喃-2-基)氧基四氢吡喃-2-基]氧基-6-甲基四氢吡喃-2-基]氧基-2,5,7,10-四羟基-2-甲基-6,11-二氧代-3,4-二氢-1H-并四苯-1-羧酸甲酯 | 1-Hydroxyauramycin A | 79217-17-7 | C41H51NO16 |
| 4-O-(吡喃葡萄糖基)-epsilon-紫红霉酮 | Methyl 2-ethyl-4-(hexopyranosyloxy)-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene-1-carboxylate | 62720-19-8 | C28H30O14 |
| 4,8,12,22,24-五羟基-10-甲氧基-1,12-二甲基-23-(甲基氨基)-20,25-二氧杂六环[19.3.1.02,19.05,18.07,16.09,14]二十五-2,4,7(16),8,14,18-己烯-6,17-二酮 | Decilorubicin | 86016-61-7 | C60H82N4O26 |
| 4'-脱氧柔红霉素 | 4'-Deoxydaunomycin | 63568-77-4 | C27H30ClNO9 |
| 3-羟基乙酰基-3,5,12-三羟基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-氨基-2,3,6-三脱氧-4-O-甲基吡喃己糖苷 | 4-Demethoxy-4'-O-methyldoxorubicin | 87471-33-8 | C27H29NO10 |
| 3-羟基乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基2,3,6-三脱氧-3-(4-吗啉基)吡喃己糖苷 | 3'-deamino-3'-(4-morpholinyl)doxorubicin hydrochloride | 89196-04-3 | C31H35NO12*ClH |
| 3-氟-4-去甲氧基柔红霉素 | 3-FD-Daunomycin | 118243-77-9 | C26H26FNO9 |
| 3-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(3-氰基-4-吗啉基)-2,3,6-三脱氧吡喃己糖苷 | 4-[6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]morpholine-3-carbonitrile | 89617-36-7 | C32H34N2O11 |
| 3-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(3-氰基-4-吗啉基)-2,3,6-三脱氧吡喃己糖苷 | Cyanomorpholinodaunomycin | 89164-74-9 | C32H34N2O11 |
| 3-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基2,3,6-三脱氧-3-[(N,N-二甲基甘氨酰甘氨酰)氨基]吡喃己糖苷 | N-[6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-3-hydroxy-2-methyloxan-4-yl]-2-[[2-(dimethylamino)acetyl]amino]acetamide;hydrochloride | 58161-65-2 | C33H40ClN3O12 |
| 3-乙酰基-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基2,3,6-三脱氧-3-[(5E,8E,11E,14E)-5,8,11,14-二十碳四烯酰氨基]吡喃己糖苷 | (5E,8E,11E,14E)-N-[6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-3-hydroxy-2-methyloxan-4-yl]icosa-5,8,11,14-tetraenamide | 86589-37-9 | C47H59NO11 |
| 3-(5-(((3-氨基-3-亚氨基丙基)氨基)羰基)-1-甲基-1H-吡咯-3-基)-2-(甲酰基氨基)噻唑 | Epelmycin E | 138636-10-9 | C42H53NO16 |
| 3-(4-氯苯基)-5-(三氟甲基)-1H-吡唑 | 4,6,9,10-tetrahydroxy-7-(4-hydroxy-3,5-dimethoxy-6-methyloxan-2-yl)oxy-2,8-dimethoxy-9-methyl-8,10-dihydro-7H-tetracene-5,12-dione | 75086-97-4 | C29H34O13 |
| 3-(1,2-二羟基乙基)-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1,2,3,4,6,11-六氢-1-并四苯基3-(苄基氨基)-2,3,6-三脱氧吡喃己糖苷 | (7S,9S)-7-[4-(benzylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-9-(1,2-dihydroxyethyl)-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride | 70844-19-8 | C34H38ClNO11 |
| 3,3'-(1,4-亚苯基二(亚甲基亚氨基))二((1S,3S)-3-乙酰基-1,2,3,4,6,11-六氢-3,5,12-三羟基-10-甲氧基-6,11-二氧代-1-并四苯基2,3,6-三脱氧-alpha-L-来苏-吡喃己糖苷 | 4-methylbenzyl-N-bis[daunorubicin] | 186131-38-4 | C62H64N2O20 |
| 3'-表柔红霉素 | Daunomycin | 66322-65-4 | C27H29NO10 |
| 3'-羟基柔红霉素 | 3'-Hydroxydaunorubicin | 64842-75-7 | C27H28O11 |
| 3'-(4-吗啉基)-3'-去氨基柔红霉素 | 3'-deamino-3'-morpholinodaunoribicin | 79867-78-0 | C31H35NO11 |
| 2H-吡喃-3-羧酸,4-氨基四氢-2,5-二甲基-6-羰基-,(2S,3R,4R,5R)- | Sulfurmycin F | 83829-33-8 | C43H55NO16 |
| 2-苯甲基乙酰基-辅酶A | 7-[(4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-9-(1,2-dihydroxyethyl)-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione | 141434-67-5 | C27H31NO11 |
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