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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 蒽环类药物

    蒽环类药物

    中文名称 英文名称 CAS号 化学式
    —— 2-[[[2-[[2-[(2R,4R)-4-[(2R,6R)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]amino]-2-carboxyethyl]-hydroxyphosphoryl]methyl]pentanedioic acid —— C36H43N2O18P
    —— 3-acetamido-4-[[4-[(2Z)-2-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]hydrazinyl]-1-[3-(2-methoxyethoxy)propylamino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid —— C43H56N6O18
    —— 3-acetamido-4-[[4-[(2Z)-2-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]hydrazinyl]-1-[3-(2-methoxyethoxy)propylamino]-1,4-dioxobutan-2-yl]amino]-4-oxobutanoic acid;3-[[2-acetamido-4-[(2Z)-2-[5-[2-[[(4E,6Z,10E)-9-carbamoyloxy-13-hydroxy-8,14-dimethoxy-4,10,12,16-tetramethyl-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),4,6,10,18-pentaen-19-yl]amino]ethoxy]-5-oxopentan-2-ylidene]hydrazinyl]-4-oxobutanoyl]amino]-4-[3-(2-methoxyethoxy)propylamino]-4-oxobutanoic acid —— C94H132N14O36
    —— 8-[2-[2-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]hydrazinyl]acetyl]-6-(2-hydrazinylacetyl)-10-(2-hydroxypropylcarbamoyl)-4,4,6,8,10-pentamethyl-3-oxododecanoic acid;hydrochloride —— C52H75ClN6O17
    —— 4-[2-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hydrazinyl]-4-oxobutanoic acid —— C31H35N3O13
    —— 3-(3-ethylsulfanyl-2,5-dihydroxypyrrol-1-yl)-N-[(2S,3S,4S)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]benzamide —— C39H38N2O13S
    —— (2S)-5-[[(1R)-2-[1-[3-[2-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hydrazinyl]-3-oxopropyl]-2,5-dihydroxypyrrol-3-yl]sulfanyl-1-carboxyethyl]amino]-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-5-oxopentanoic acid —— C56H60N12O20S
    —— (7S,9S)-7-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;2-methylidene-4-oxo-1H-pyrimidine-6-carboxylic acid —— C33H35N3O14
    —— (7S,9S)-9-acetyl-6,9,11-trihydroxy-7-[5-hydroxy-6-methyl-4-[(2-nitrophenyl)methylamino]oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C34H35ClN2O12
    —— N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-[2-[[amino-(octadeca-9,12-dienylamino)methylidene]amino]acetyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-methylboronamidic acid —— C47H67BN4O11
    —— (7S,9S)-7-[(2S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-9-propanoyl-8,10-dihydro-7H-tetracene-5,12-dione —— C28H31NO10
    —— (8R,10S)-10-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6-ethoxy-11-hydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione;N-[(2S,3R,4S,6S)-6-[[(1S,3R)-3-[2-(1,1-diphenylpropoxy)acetyl]-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-1-yl]oxy]-2,3-dimethyloxan-4-yl]-2,2,2-trifluoroacetamide —— C74H77F3N2O20
    —— methyl (1R,2R,4S)-4-[(2R,4R,5S)-4-(dimethylamino)-5-[(2S,4R,5S)-4-hydroxy-6-methyl-5-[[6-methyl-5-(2-propanoylhydrazinyl)-3,4-dihydro-2H-pyran-2-yl]oxy]oxan-2-yl]oxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C45H59N3O15
    —— (2S)-N-[3-hydroxy-1-[[(2S)-1-[[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]-2-(methylamino)pentanediamide —— C42H55N5O16
    —— methyl (1R,2R,4S)-4-[(2R,4R)-5-[(2S,4R)-5-[[(2R)-5-(2-acetylhydrazinyl)-6-methyl-3,4-dihydro-2H-pyran-2-yl]oxy]-4-hydroxy-6-methyloxan-2-yl]oxy-4-(dimethylamino)-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C44H57N3O15
    —— methyl (1R,2R)-2-ethyl-2,5,7-trihydroxy-4-[5-[4-hydroxy-6-methyl-5-(6-methyl-5-oxooxan-2-yl)oxyoxan-2-yl]oxy-6-methyloxan-2-yl]oxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C40H48O15
    —— (7S,9S)-7-[(5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C27H29NO11
    —— 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-[2-(1-hydroxyethoxy)acetyl]-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C29H33NO12
    —— (7S,9S)-9-acetyl-6,9,11-trihydroxy-7-[5-hydroxy-6-methyl-4-[(4-nitrophenyl)methylamino]oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C34H35ClN2O12
    —— 9-acetyl-7-[[5-hydroxy-2-(2-hydroxypropyl)-4,10-dimethyl-4,5,6,6a,7,8,10,10a-octahydropyrano[3,4-d][1,3,6]dioxazocin-8-yl]oxy]-6,9,11-tris(hydroxymethoxy)-8,10-dihydro-7H-tetracene-5,12-dione —— C36H45NO15
    —— (7S,9S)-7-[(2R,4R,5S)-4-(2,3-dihydropyrrol-1-yl)-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C31H33NO11
    —— 2-[[6-[[(3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]carbamoyloxy]ethanesulfinic acid —— C30H33NO14S
    —— 2-[[6-[[(3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]carbamoyloxy]ethanesulfinate —— C30H32NO14S-
    —— 2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-[[3-(3-carboxypropanoyloxymethoxycarbonyl)-4-[(2-oxo-1,3,2lambda5-dioxaphosphinan-2-yl)oxy]phenyl]methoxycarbonyl]amino]benzoyl]amino]-5-[2-[2-[2-[2-[[2-[2-[[2-[2-[2-[2-[2-[2-[2-[4-[[1-carboxy-2-[[1-[3-(1H-imidazol-2-ylamino)propyl]indazole-5-carbonyl]amino]ethyl]sulfamoyl]phenoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethyl-[2-[2-[2-[3-[4-[4-(4-chlorophenoxy)phenyl]sulfonyl-4-(hydroxycarbamoyl)oxan-2-yl]propanoylamino]ethoxy]ethoxy]ethyl]amino]-2-oxoethoxy]ethoxymethyl-hydroxyphosphoryl]methoxy]ethoxy]acetyl]-[2-[2-[2-[[2-[2-[N-[2-[4-[4-(2,3-dihydropyrrol-1-yl)-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethoxy]carbonyl-2-[[3-(dimethylamino)-3-oxopropyl]disulfanyl]anilino]ethoxy]acetyl]amino]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethylamino]-5-oxopentanoic acid —— C167H211ClN24O64P2S4
    —— 2-[[2-methylpropanoyl(phosphanylidene)-lambda4-sulfanyl]diazenyl]-2-[(2S,4S)-2,5,12-trihydroxy-4-(5-hydroxy-6-methyloxan-2-yl)oxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]acetaldehyde —— C31H35N2O11PS
    —— 6-(2,5-dioxocyclopent-3-en-1-yl)-N-[2-[(2R,4S)-2,5,12-trihydroxy-4-(5-hydroxy-4,6-dimethyloxan-2-yl)oxy-7-methyl-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]prop-1-enyl]hexanamide —— C40H45NO11
    —— 9H-fluoren-9-ylmethyl 5-[2-[[1-[[1-[[2-[[(2S)-5-amino-1-[[3-hydroxy-1-[[(2S)-1-[[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-cyclohexyl-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-4-hydroxypyrrolidin-1-yl]-5-oxopentanoate —— C79H99N9O25
    —— (8R,10S)-10-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6-ethoxy-11-hydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione;N-[(2S,3S,4S,6S)-6-[[(1S,3R)-3-[2-(1,1-diphenylethoxy)acetyl]-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-1-yl]oxy]-2,3-dimethyloxan-4-yl]-2,2,2-trifluoroacetamide —— C73H75F3N2O20
    —— N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-3-[4-(2,5-dioxopyrrol-1-yl)phenyl]propanehydrazide —— C40H40N4O13
    —— [4-[3-[2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethoxy]-3-oxoprop-1-enyl]-2-methoxyphenyl] 4-nitrooxybutanoate —— C41H42N2O18
    —— [2-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] 4-[2,5-dihydroxy-3-(2-oxopropyl)pyrrol-1-yl]butanoate —— C38H42N2O15
    —— N'-[1-[(2S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-6-(2,5-dioxopyrrol-1-yl)hexanehydrazide —— C37H42N4O13
    —— N'-[1-[(2R,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]octadecanehydrazide —— C45H65N3O11
    —— 3,12-dihydroxy-3-(2-hydroxyacetyl)-1-(5-hydroxy-4,6-dimethyloxan-2-yl)oxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracene-5-carbaldehyde —— C29H30O11
    —— 9H-fluoren-9-ylmethyl 3-oxobutanoate;(7S,9S)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-7-[5-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C46H47NO14
    —— 3-oxobutanoic acid;(7S,9S)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-7-[5-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C32H37NO14
    —— [2-[4-[4-[(2,2-difluoroacetyl)amino]-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl] pentanoate —— C34H37F2NO13
    —— 9-acetyl-7-[4-amino-6-(fluoromethyl)-5-hydroxyoxan-2-yl]oxy-6,9-dihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;9-acetyl-7-[6-(fluoromethyl)-5-hydroxy-4-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C55H57F2NO19
    —— (2,5-dioxocyclopentyl) 2-[[2-hydroxy-1-[(2S,4S)-2,5,12-trihydroxy-4-[5-hydroxy-6-methyl-4-[(2,2,2-trifluoroacetyl)amino]oxan-2-yl]oxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylidene]amino]oxyacetate —— C36H35F3N2O16
    —— [3-[4-[[(2S,3S,4S,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-oxobutanoyl]oxy-2-octadec-9-enoyloxypropyl] octadec-9-enoate —— C70H103NO18
    —— 4-[[2,5-dihydroxy-3-[2-(methylamino)-2-oxoethyl]sulfanylpyrrol-1-yl]methyl]-N-[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]cyclohexane-1-carboxamide —— C42H49N3O15S
    —— (7S,9R)-7-(4,5-dihydroxy-3-methoxy-6-methyloxan-2-yl)oxy-4,6,9-trihydroxy-2-methoxy-9-methyl-8,10-dihydro-7H-tetracene-5,12-dione —— C27H30O11
    —— methyl (10S,12S,13R)-23-(dimethylamino)-4,8,12,22,24-pentahydroxy-1,12-dimethyl-6,17-dioxo-10-(3,4,5-trimethoxy-4,6-dimethyloxan-2-yl)oxy-20,25-dioxahexacyclo[19.3.1.02,19.05,18.07,16.09,14]pentacosa-2,4,7(16),8,14,18-hexaene-13-carboxylate —— C39H49NO16
    —— methyl (1R,2R,4S)-4-[5-(4,5-dihydroxy-6-methyloxan-2-yl)oxy-4-hydroxy-6-methyloxan-2-yl]oxy-2,5,7-trihydroxy-2-methyl-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C33H38O14
    —— methyl (1R,2R,4S)-4-[4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7-trihydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C30H35NO10
    —— 6,9,11-trihydroxy-9-(2-hydroxyacetyl)-7-[5-hydroxy-6-methyl-4-(2-oxononadec-10-enyl)oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C46H62O12
    —— (2,5-Dihydroxypyrrol-1-yl) 2-[1-[2-[5,12-dihydroxy-7-methoxy-4-(6-methyl-5-morpholin-3-yloxyoxan-2-yl)oxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-2-yl]-2-oxoethoxy]cyclohexyl]oxyacetate —— C43H50N2O16
    —— (2,5-dihydroxypyrrol-1-yl) 2-[[6-[2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethoxy]oxan-2-yl]methoxy]acetate —— C44H50N2O19
    —— 6-(2,5-dioxopyrrol-1-yl)-N'-[2-oxo-1-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethyl]hexanehydrazide —— C42H48N4O15
    —— N-[(E,4R,5S)-5-amino-4,6-dihydroxyhex-2-enyl]-3-[1-[[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]methyl]-2,5-dioxopyrrolidin-3-yl]sulfanylpropanamide;1-[2-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]ethyl]pyrrole-2,5-dione —— C74H84N6O29S