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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 蒽环类药物

    蒽环类药物

    中文名称 英文名称 CAS号 化学式
    —— (2R)-2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methylamino]benzoyl]amino]-8-[2-[[3-hydroxy-2-methyl-6-[[(1R)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyloxy]ethyldisulfanyl]-5-oxooctanoic acid;2-[2-[[2-[2-(2,6-dichloroanilino)phenyl]acetyl]carbamoyloxy]ethyldisulfanyl]ethyl 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazole-1-carboxylate;2-[2-[2-[2-(2,6-dichloroanilino)phenyl]acetyl]oxyethyldisulfanyl]ethyl 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazole-1-carboxylate;2-[2-[5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazole-1-carbonyl]oxyethyldisulfanyl]ethyl (5R,6R)-6-[3-amino-3-(4-hydroxyphenyl)-2-oxopropyl]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate —— C164H174Cl4N22O43S12
    —— 13-methylnonadec-9-enyl N-[4-[[3-hydroxy-2-methyl-6-[[3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-oxobutyl]carbamate —— C52H74N2O14
    —— [4-[[6-amino-2-[[(2S)-2-[6-[6-(2,5-dioxopyrrol-1-yl)hexanoylamino]hexanoylamino]-3-phenylpropanoyl]amino]hexanoyl]amino]phenyl]methyl N-[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamate —— C66H79N7O19
    —— 6-N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hexanedihydrazide —— C33H41N5O12
    —— (7S,9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-9-methyl-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C26H30ClNO9
    —— (7R)-9-acetyl-7-(4-amino-6-methyl-5-phenylmethoxyoxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C34H36ClNO10
    —— (2,5-dihydroxypyrrol-1-yl) 2-[[6-[2-(5,12-dihydroxy-7-methoxy-2-methyl-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl)-2-oxoethoxy]oxan-2-yl]methoxy]acetate —— C34H35NO13
    —— N-[(Z)-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-4-oxopentanamide —— C32H37N3O12
    —— (2R)-2-acetamido-3-[[3-oxo-3-[2-[2-oxo-1-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(2S,4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethyl]hydrazinyl]propyl]disulfanyl]propanoic acid —— C40H48N4O16S2
    —— N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-4-oxopentanehydrazide —— C32H37N3O12
    —— (7R)-9-acetyl-7-[4-amino-5-[(2,6-difluorophenyl)methoxy]-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C34H34ClF2NO10
    —— 6-(2-acetylhydrazinyl)-N-[(Z)-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-6-oxohexanamide —— C35H43N5O13
    —— (1S,3S)-3-acetyl-3,11-dihydroxy-1-[4-(hydroxyamino)-6-methyl-5-oxooxan-2-yl]oxy-10-methoxy-6-sulfanyl-2,4-dihydro-1H-tetracene-5,12-dione —— C27H27NO10S
    —— 4-[(3S,4R,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]morpholine-3-carbonitrile —— C32H34N2O12
    —— 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,11-dihydroxy-9-(2-hydroxyacetyl)-9-(hydroxymethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C28H31NO11
    —— 2-[1-[[4-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyl]cyclohexyl]methyl]-2-methylidene-5-oxopyrrolidin-3-yl]sulfanylacetic acid;N-[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]-4-[(2-methylidene-5-oxopyrrol-1-yl)methyl]cyclohexane-1-carboxamide —— C82H92N4O28S
    —— N'-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-6-(2,5-dioxopyrrol-1-yl)hexanehydrazide —— C37H42N4O13
    —— (2S)-2-[[(2S)-2-[[(2R)-2-amino-3-[2,5-dihydroxy-1-[3-[[(2S,3S,4S)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyl]phenyl]pyrrol-3-yl]sulfanylpropanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-N-[(3S)-4-methyl-2-oxohexan-3-yl]pentanediamide —— C59H74N10O19S
    —— (2S,3S,4S,5R,6S)-6-[[(1S,4aS,11aR,12aS)-8-[[2-(tert-butylamino)acetyl]amino]-3-carbamoyl-1,10-bis(dimethylamino)-7-hydroxy-2,4,5,6-tetraoxo-1,5a,11,11a,12,12a-hexahydrotetracen-4a-yl]oxy]-3,4,5-trihydroxyoxane-2-carboxylic acid —— C35H47N5O14
    —— N-[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]-4,8,13,17,21-pentamethyldocosa-4,8,12,16,20-pentaenamide —— C54H71NO12
    —— N-[6-[[(1S,3S)-3-[N-[2-[[(2S)-1-[[(2S)-1-[(2-amino-2-oxoethyl)amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]amino]-2-oxoethoxy]-C-methylcarbonimidoyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-5-iminohexanamide —— C49H59N7O16
    —— (8S,10S)-8-Acetyl-10-((2R,4S,5R,6S)-4-amino-5-hydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione —— C27H29NO11
    —— (7S,9S)-9-acetyl-7-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C27H30ClNO11
    —— N.N-Dimethylglycyldaunorubicin 68681-75-4 C31H36N2O11
    —— N-[(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-2-(dimethylamino)acetamide;hydrochloride —— C31H37ClN2O11
    —— doxorubicin 68833-10-3 C27H29NO11
    —— 8-Desacetyl-8-carboxy Daunorubicin Hydrochloride 58199-96-5 C26H28ClNO11
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-methoxybenzamide —— C35H37N3O11
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-methoxybenzamide;hydrochloride —— C35H38ClN3O11
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-(dimethylamino)benzamide —— C36H40N4O10
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-(dimethylamino)benzamide;hydrochloride —— C36H41ClN4O10
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-hydroxybenzamide —— C34H35N3O11
    —— [(2E)-2-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]hydrazinyl] 4-methylbenzenesulfonate —— C34H37N3O13S
    —— [(2E)-2-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylidene]hydrazinyl] 4-methylbenzenesulfonate —— C34H37N3O12S
    —— methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate;hydrochloride —— C28H32ClNO11
    —— (1R,2R,4S)-4-[(2R,3R,4S,5R)-3,4-Bis-(4-nitro-benzoyloxy)-5-(4-nitro-benzoyloxymethyl)-tetrahydro-furan-2-yloxy]-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 62720-18-7 C48H37N3O22
    —— (1R,2R,4S)-4-((2R,3R,4S,5S)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester —— C27H28O13
    —— (1R,2R,4S)-4-((2R,3R,4S,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester —— C27H28O13
    —— methyl (1R,2R,4S)-2-ethyl-2,5,7,12-tetrahydroxy-4-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]oxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C27H28O12
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-3,4-dichlorobenzamide;hydrochloride —— C34H34Cl3N3O10
    —— methyl (1R,2R,4S)-4-[(2S,4S,5R)-4,5-dihydroxyoxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C27H28O12
    —— methyl (1R,2R,4S)-2-ethyl-2,5,7,12-tetrahydroxy-4-[(2R,4S,5R)-4-(4-nitrobenzoyl)oxy-5-[(4-nitrobenzoyl)oxymethyl]oxolan-2-yl]oxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C41H34N2O18
    —— (1R,2R,4S)-4-((2R,3R,4R,5R)-3,4-Dihydroxy-5-hydroxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester —— C27H28O13
    —— (1R,2R,4S)-2-Ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2S,3R,4S,5S)-3,4,5-trihydroxy-tetrahydro-pyran-2-yloxy)-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 63252-12-0 C27H28O13
    —— (1R,2R,4S)-4-((2R,3S,4R,5R)-3,4-Bis-benzyloxy-5-benzyloxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 62751-38-6 C48H46O13
    —— (1R,2R,4S)-2-Ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-6-hydroxymethyl-tetrahydro-pyran-2-yloxy)-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 62720-19-8 C28H30O14
    —— N-[(E)-[1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-3,4-dichlorobenzamide —— C34H33Cl2N3O11
    —— methyl (1R,2R,4S)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-4-[(2R,3R,4S,5R,6R)-3,4,5-triacetyloxy-6-(acetyloxymethyl)oxan-2-yl]oxy-3,4-dihydro-1H-tetracene-1-carboxylate —— C36H38O18
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-3-nitrobenzamide;hydrochloride —— C34H35ClN4O12
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-phenylbenzamide;hydrochloride —— C40H40ClN3O10