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    首页 分子通 按分子结构分类 有机化合物 苯丙烷和聚酮 蒽环类药物

    蒽环类药物

    中文名称 英文名称 CAS号 化学式
    —— hydroxymethyl 4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracene-2-carboxylate —— C27H29NO12
    —— [6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]azanium;[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-3-propanoyl-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]azanium;dichloride —— C55H62Cl2N2O20
    —— 9-acetyl-7-[4-amino-6-(fluoromethyl)-5-hydroxyoxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;7-[6-(fluoromethyl)-5-hydroxy-4-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C55H57F2NO21
    —— (7S,9S)-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-7-[(2R,4R,5S)-5-hydroxy-6-methyl-4-morpholin-4-yloxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C31H35NO12
    —— (7S,9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;5-[[(2S)-2-cyclohexyl-2-[[(2S)-2-[[(2S)-2-[[(2S,4R)-1-[3-(9H-fluoren-9-ylmethoxy)-3-oxopropanoyl]-4-hydroxypyrrolidine-2-carbonyl]amino]propanoyl]amino]-3-hydroxypropanoyl]amino]acetyl]amino]pentanoic acid;9H-fluoren-9-ylmethyl 3-[(2S,4R)-4-hydroxy-2-[[(2S)-1-[[(2S)-3-hydroxy-1-[[5-[[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-5-oxopentyl]amino]-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidin-1-yl]-3-oxopropanoate —— C128H149N11O42
    —— 5-[2-[[1-[[1-[[2-[[(2S)-5-amino-1-[[3-hydroxy-1-[[(2S)-1-[[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-1-oxopropan-2-yl]amino]-1,5-dioxopentan-2-yl]amino]-1-cyclohexyl-2-oxoethyl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-1-oxopropan-2-yl]carbamoyl]-4-hydroxypyrrolidin-1-yl]-5-oxopentanoic acid —— C65H89N9O25
    —— 2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-[[2-methylpropanoyl(phosphanylidene)-lambda4-sulfanyl]diazenyl]acetaldehyde —— C31H36N3O11PS
    —— [(1S,3S)-3-acetyl-1-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-3,12-dihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-5-yl] 1-hydroxy-2,2,6,6-tetramethylpiperidine-4-carboxylate —— C37H46N2O12
    —— 2-[2,5-dihydroxy-1-[[4-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyl]cyclohexyl]methyl]pyrrol-3-yl]sulfanylacetic acid —— C41H46N2O16S
    —— diethyl (E)-2-[[6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-3-hydroxy-2-methyloxan-4-yl]amino]but-2-enedioate —— C35H39NO14
    —— methyl (E)-3-[[6-[(3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl)oxy]-3-hydroxy-2-methyloxan-4-yl]amino]but-2-enoate —— C32H35NO12
    —— 9-acetyl-6,9,11-trihydroxy-7-[5-hydroxy-6-methyl-4-[[(E)-4-oxo-4-phenylbut-2-en-2-yl]amino]oxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C37H37NO11
    —— 3-acetamido-4-[[(3S,4R,6R)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino]-4-oxobutanoic acid —— C33H36N2O15
    —— N-[6-[[(1S,3S)-3-formyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-4-[[3-[2-(methylamino)-2-oxoethyl]sulfanyl-2-methylidene-5-oxopyrrolidin-1-yl]methyl]cyclohexane-1-carboxamide;methanol —— C43H53N3O14S
    —— [4-[[6-amino-2-[[(2S)-2-[[(2R)-2-amino-3-phenylpropanoyl]amino]-3-phenylpropanoyl]amino]hexanoyl]amino]phenyl]methyl N-[3-hydroxy-2-methyl-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamate —— C59H66N6O16
    —— N'-[1-[(2R,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-6-oxo-4-(phenylhydrazinylidene)naphthalene-2-sulfonohydrazide —— C43H41N5O13S
    —— [(2S,3S,4S,6R)-6-[[(1S,3S)-3-acetyl-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-2-methyl-4-(methylamino)oxan-3-yl] N-(2,3-dihydroxypropyl)-N-methylcarbamate;3-(methylamino)propane-1,2-diol;(4-nitrophenyl) carbonochloridate —— C44H55ClN4O19
    —— (2,5-dihydroxypyrrol-1-yl) 2-[1-[2-oxo-2-[(2S,4S)-2,5,12-trihydroxy-7-methoxy-4-[[(4R,6S,7S,9R,10S)-10-methoxy-6-methyl-5,8,11-trioxa-1-azatricyclo[7.4.0.02,7]tridecan-4-yl]oxy]-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethoxy]cyclohexyl]oxyacetate —— C44H50N2O18
    —— (9S)-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-9-(2-methoxyacetyl)-8,10-dihydro-7H-tetracene-5,12-dione —— C28H31NO11
    —— benzyl (2S)-2-[[(2S)-1-[[2-[(2S)-2-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methyl-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]amino]-1-oxopropan-2-yl]carbamoyl]pyrrolidine-1-carboxylate;benzyl N-[2-[(2S)-2-[[3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methyl-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyl]pyrrolidin-1-yl]-2-oxoethyl]carbamate —— C92H102N8O30
    —— (7S,9S)-9-acetyl-7-[(2S,4S,5S,6S)-4-amino-5,6-dimethyloxan-2-yl]oxy-6,9,11-trihydroxy-8,10-dihydro-7H-tetracene-5,12-dione;(7S,9S)-9-acetyl-6,9,11-trihydroxy-7-[(2R,4S,5S,6S)-5-hydroxy-4,6-dimethyloxan-2-yl]oxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C55H59NO18
    —— N'-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-2-[(3,5-dibromo-4-hydroxy-6-methylidenecyclohexa-2,4-dien-1-ylidene)-(3,5-dibromo-4-hydroxy-2-methylphenyl)methyl]benzenesulfonohydrazide —— C48H43Br4N3O14S
    —— (2R)-3-[2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]sulfanyl-2-methylpropanamide —— C31H36N2O11S
    —— [4-[3-[2-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethoxy]-3-oxoprop-1-enyl]-2-methoxyphenyl] 4-[hydroxy(nitro)amino]oxybutanoate —— C41H43N3O19
    —— (1S,3R)-3-acetyl-11-amino-1-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-3,6-dihydroxy-10-methoxy-2,4-dihydro-1H-tetracene-5,12-dione —— C27H30N2O9
    —— N'-[1-[(2S,4S)-4-[(2R,4R,5S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-4-[(2,5-dioxopyrrol-1-yl)methyl]cyclohexane-1-carbohydrazide —— C39H44N4O13
    —— (7S,9R)-9-acetyl-7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione —— C27H29NO10
    —— ethyl 2-[[8-acetyl-10-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-8,12-dihydroxy-1-methoxy-6,11-dioxo-9,10-dihydro-7H-tetracen-5-yl]amino]but-2-enoate —— C33H38N2O11
    —— [3,5-dimethyl-4-(propylcarbamoyloxy)phenyl]methyl [[(2S,6S)-3-hydroxy-2-methyl-6-[[(1S,3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]amino] carbonate —— C41H46N2O16
    —— N'-[6-[[3-[(E)-N-(cyclohexylideneamino)-C-methylcarbonimidoyl]-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]-3-hydroxy-2-methyloxan-4-yl]-N,N-dimethylmethanimidamide —— C36H44N4O9
    —— tert-butyl N-[(E)-1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]carbamate —— C31H37N3O11
    —— (8R,10S)-10-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-11-hydroxy-8-(2-hydroxyacetyl)-1-methoxy-6-methyl-7,8,9,10-tetrahydrotetracene-5,12-dione;(8R,10S)-6,11-dihydroxy-8-(2-hydroxyacetyl)-10-[(2R,4S,5R,6S)-5-hydroxy-6-methyl-4-(methylamino)oxan-2-yl]oxy-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione —— C56H62N2O19
    —— 7-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;N-[(Z)-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]amino]-4-oxopentanamide;4-[(2E)-2-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-hydroxyethylidene]hydrazinyl]-4-oxobutanoic acid;ethane —— C92H107N7O36
    —— N'-[1-[(2S,4S)-4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]-3-hydroxypropanehydrazide —— C30H35N3O12
    —— 2-[[4-[(2-amino-4-oxo-3H-pteridin-6-yl)methyl-[[3-(3-carboxypropanoyloxymethoxycarbonyl)-4-[(2-oxo-1,3,2lambda5-dioxaphosphinan-2-yl)oxy]phenyl]methoxycarbonyl]amino]benzoyl]amino]-5-[2-[2-[2-[2-[[2-[2-[[2-[2-[2-[2-[2-[2-[2-[4-[[1-carboxy-2-[[1-[3-(1H-imidazol-2-ylamino)propyl]indazole-5-carbonyl]amino]ethyl]sulfamoyl]phenoxy]ethoxy]ethylamino]-2-oxoethoxy]ethoxy]ethyl-[2-[2-[2-[3-[4-[4-(4-chlorophenoxy)phenyl]sulfonyl-4-(hydroxycarbamoyl)piperidin-1-yl]propanoylamino]ethoxy]ethoxy]ethyl]amino]-2-oxoethoxy]ethoxymethyl-hydroxyphosphoryl]methoxy]ethoxy]acetyl]-[2-[2-[2-[[2-[2-[N-[2-[4-[4-(2,3-dihydropyrrol-1-yl)-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethoxy]carbonyl-2-[[3-(dimethylamino)-3-oxopropyl]disulfanyl]anilino]ethoxy]acetyl]amino]ethoxy]ethoxy]ethyl]amino]ethoxy]ethoxy]ethoxy]ethylamino]-5-oxopentanoic acid —— C167H212ClN25O63P2S4
    —— 3,4,5-trihydroxy-6-[4-[[3-hydroxy-2-methoxy-6-[[(3S)-3,5,12-trihydroxy-3-(2-hydroxyacetyl)-10-methoxy-6,11-dioxo-2,4-dihydro-1H-tetracen-1-yl]oxy]oxan-4-yl]carbamoyloxymethyl]-2-nitrophenoxy]oxane-2-carboxylic acid —— C41H42N2O23
    —— 2-[4-[2-[2-(2-acetamidoethoxy)ethoxy]ethylcarbamoyl]-2-[[3-[2-[1-[4-(4-amino-5-hydroxy-6-methyloxan-2-yl)oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]-2-oxoethyl]hydrazinyl]-3-oxopropyl]carbamoyl]-7-[2-[2-[2-(2-ethenylsulfonylethoxycarbonylamino)ethoxy]ethoxy]ethylamino]-7-oxoheptyl]-4-[14-(1,5-dicarboxypentan-3-yl)-6-tricyclo[10.4.0.04,9]hexadeca-1(12),4(9),5,7,13,15-hexaenyl]heptanedioic acid —— C88H118N8O31S
    —— (8R,10S)-10-[(2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-6-ethoxy-11-hydroxy-8-(2-hydroxyacetyl)-1-methoxy-7,8,9,10-tetrahydrotetracene-5,12-dione;N-[(2S,3R,4S,6S)-6-[[(1S,3R)-3-[2-(1,1-diphenylethoxy)acetyl]-5,12-dihydroxy-10-methoxy-6,11-dioxo-1,2,3,4-tetrahydrotetracen-1-yl]oxy]-2,3-dimethyloxan-4-yl]-2,2,2-trifluoroacetamide —— C73H75F3N2O20
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-ethylbenzamide;hydrochloride —— C36H40ClN3O10
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-hydroxybenzamide;hydrochloride —— C34H36ClN3O11
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-butoxybenzamide;hydrochloride —— C38H44ClN3O11
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-ethylbenzamide —— C36H39N3O10
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-butoxybenzamide —— C38H43N3O11
    —— (7S,9S)-7-[(2R,4S,5S,6S)-4-(dibenzylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-9-(1-hydroxyethyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione;hydrochloride —— C41H44ClNO10
    —— (1R,2R,4S)-2-Ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-4-((2R,3S,4R,5S,6S)-3,4,5-trihydroxy-6-methyl-tetrahydro-pyran-2-yloxy)-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester 63252-11-9 C28H30O13
    —— N-[(E)-1-[(2S,4S)-4-[(2R,4S,5S,6S)-4-amino-5-hydroxy-6-methyloxan-2-yl]oxy-2,5,12-trihydroxy-7-methoxy-6,11-dioxo-3,4-dihydro-1H-tetracen-2-yl]ethylideneamino]-4-chlorobenzamide —— C34H34ClN3O10
    —— (1R,2R,4S)-4-((2R,3R,4R,5R)-3,4-Bis-benzoyloxy-5-benzoyloxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester —— C48H40O16
    —— (1R,2R,4S)-4-((2R,3R,4R,5S)-3,4-Bis-benzoyloxy-5-benzoyloxymethyl-tetrahydro-furan-2-yloxy)-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-naphthacene-1-carboxylic acid methyl ester —— C48H40O16
    —— methyl (1R,2R,4S)-4-[(2R,4S,5S,6S)-4,5-dihydroxy-6-methyloxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C28H30O12
    —— methyl (1R,2R,4S)-4-[(2S,4S,5R)-4,5-diacetyloxyoxan-2-yl]oxy-2-ethyl-2,5,7,12-tetrahydroxy-6,11-dioxo-3,4-dihydro-1H-tetracene-1-carboxylate —— C31H32O14