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    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(2-(4-(pyrrolidin-1-yl)piperidin-1-yl)ethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C40H47FN6O3S
    N-((1s,4s)-4-(5-fluoro-2-(4'-(2-(4-(pyrrolidin-1-yl)piperidin-1-yl)ethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— 3'-(5-fluoro-3-((1s,4s)-4-(5-methylimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)-2-(morpholinomethyl)biphenyl-4-carboxylic acid —— C39H39FN6O6
    3'-(5-fluoro-3-((1s,4s)-4-(5-methylimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)-2-(morpholinomethyl)biphenyl-4-carboxylic acid
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-((4-(pyrrolidin-1-yl)piperidin-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C43H48FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-((4-(pyrrolidin-1-yl)piperidin-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-3'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C40H44FN7O4
    N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-3'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(3'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C40H44FN7O4
    N-((1s,4s)-4-(2-(3'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-(trifluoromethyl)thiazole-4-carboxamide —— C34H33F4N5O5S
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-(trifluoromethyl)thiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-hydroxyquinoline-3-carboxamide —— C39H38FN5O6
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-hydroxyquinoline-3-carboxamide
    —— N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-6-fluoroimidazo[1,2-a]pyridine-2-carboxamide —— C38H38F2N6O5
    N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-6-fluoroimidazo[1,2-a]pyridine-2-carboxamide
    —— N<sup>2</sup>-Ethoxycarbonyl-N<sup>1</sup>-methyl-N<sup>1</sup>-nitroformamidine —— C5H9N3O4
    N<sup>2</sup>-Ethoxycarbonyl-N<sup>1</sup>-methyl-N<sup>1</sup>-nitroformamidine
    —— N-((1s,4s)-4-(2-(4'-(2-((3S,5R)-3,5-dimethylpiperazin-1-yl)ethyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)quinoxaline-2-carboxamide —— C41H44FN7O3
    N-((1s,4s)-4-(2-(4'-(2-((3S,5R)-3,5-dimethylpiperazin-1-yl)ethyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)quinoxaline-2-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(piperazin-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C40H44FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(piperazin-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-2'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C36H41FN6O4S
    N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-2'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— 2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-N-((1s,4s)-4-(1,5-dimethyl-1H-pyrazole-3-carboxamido)cyclohexyl)-5-fluoronicotinamide —— C36H41FN6O5
    2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-N-((1s,4s)-4-(1,5-dimethyl-1H-pyrazole-3-carboxamido)cyclohexyl)-5-fluoronicotinamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C40H44FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— 1-(4-methoxy-phenyl)-N3-phenyl-1H-[1,2,4]triazole-3,5-diamine —— C15H15N5O
    1-(4-methoxy-phenyl)-N3-phenyl-1H-[1,2,4]triazole-3,5-diamine
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)quinoline-2-carboxamide —— C41H43FN6O4
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)quinoline-2-carboxamide
    —— N-((1s,4s)-4-(2-(4'-(3-(1,4-diazepan-1-yl)propyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C37H43FN6O3S
    N-((1s,4s)-4-(2-(4'-(3-(1,4-diazepan-1-yl)propyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C36H41FN6O4S
    N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C39H41FN6O5
    N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— 2-chloroethyl 3-nitro-3-azabut-2-yl ether —— C5H11ClN2O3
    2-chloroethyl 3-nitro-3-azabut-2-yl ether
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(2-(piperazin-1-yl)ethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)quinoxaline-2-carboxamide —— C39H40FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-(2-(piperazin-1-yl)ethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)quinoxaline-2-carboxamide
    —— n-butyl 3-[4-(1-n-hexadecylpiperazin-4-yl)-phenyl]-propionate —— C33H58N2O2
    n-butyl 3-[4-(1-n-hexadecylpiperazin-4-yl)-phenyl]-propionate
    —— silver monohydride —— AgH
    silver monohydride
    —— N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C40H44FN7O3
    N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-3'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)pyrazolo[1,5-a]pyridine-2-carboxamide —— C39H42FN7O4
    N-((1s,4s)-4-(2-(4'-(((3S,5R)-3,5-dimethylpiperazin-1-yl)methyl)-3'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)pyrazolo[1,5-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-6-methylpicolinamide —— C37H40FN5O5
    N-((1s,4s)-4-(2-(2'-((1,4-oxazepan-4-yl)methyl)-4'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-6-methylpicolinamide
    —— 6-fluoro-N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)imidazo[1,2-a]pyridine-2-carboxamide —— C37H36F2N6O4S
    6-fluoro-N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)imidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(2'-hydroxy-4'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C34H37FN6O4S
    N-((1s,4s)-4-(5-fluoro-2-(2'-hydroxy-4'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(4-methyl-1,4-diazepan-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C38H45FN6O3S
    N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(4-methyl-1,4-diazepan-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-3-hydroxypicolinamide —— C35H36FN5O6
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-3-hydroxypicolinamide
    —— N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-5'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C36H41FN6O4S
    N-((1s,4s)-4-(2-(3'-(((3R,5S)-3,5-dimethylpiperazin-1-yl)methyl)-5'-hydroxybiphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(2-(4'-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C38H45FN6O3S
    N-((1s,4s)-4-(2-(4'-(3-((3S,5R)-3,5-dimethylpiperazin-1-yl)propyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine-2-carboxamide —— C37H42FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5,6,7,8-tetrahydro-imidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(4'-((1,4-oxazepan-4-yl)methyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C39H41FN6O4
    N-((1s,4s)-4-(2-(4'-((1,4-oxazepan-4-yl)methyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(1,5-dimethyl-1H-pyrazole-3-carboxamido)cyclohexyl)-5-fluoro-2-(4'-hydroxy-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamide —— C35H39FN6O4S
    N-((1s,4s)-4-(1,5-dimethyl-1H-pyrazole-3-carboxamido)cyclohexyl)-5-fluoro-2-(4'-hydroxy-2'-(thiomorpholinomethyl)biphenyl-3-yloxy)nicotinamide
    —— N-((1s,4s)-4-(5-fluoro-2-(3'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C38H40FN7O3
    N-((1s,4s)-4-(5-fluoro-2-(3'-(piperazin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— 5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)-N-((1s,4s)-4-(2-hydroxy-5-methylbenzamido)cyclohexyl)nicotinamide —— C37H39FN4O6
    5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)-N-((1s,4s)-4-(2-hydroxy-5-methylbenzamido)cyclohexyl)nicotinamide
    —— dl-trans-2-benzyloxymethyl-3-hydroxytetrahydropyran —— C13H18O3
    dl-trans-2-benzyloxymethyl-3-hydroxytetrahydropyran
    —— 2-bromo-4-n-butoxyphenol —— C10H13BrO2
    2-bromo-4-n-butoxyphenol
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-((4-isopropylpiperazin-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C37H43FN6O4S
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-((4-isopropylpiperazin-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— 3-(3'-(5-fluoro-3-((1s,4s)-4-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)biphenyl-4-yl)propyl methanesulfonate —— C36H40FN5O6S
    3-(3'-(5-fluoro-3-((1s,4s)-4-(5,6,7,8-tetrahydroimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)biphenyl-4-yl)propyl methanesulfonate
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(pyrrolidin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide —— C38H39FN6O3
    N-((1s,4s)-4-(5-fluoro-2-(4'-(pyrrolidin-1-ylmethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-5-methylimidazo[1,2-a]pyridine-2-carboxamide
    —— N-((1s,4s)-4-(2-(4'-(2-((3S,5R)-3,5-dimethylpiperazin-1-yl)ethyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C37H43FN6O3S
    N-((1s,4s)-4-(2-(4'-(2-((3S,5R)-3,5-dimethylpiperazin-1-yl)ethyl)biphenyl-3-yloxy)-5-fluoronicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(2'-hydroxy-4'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C34H36FN5O5S
    N-((1s,4s)-4-(5-fluoro-2-(2'-hydroxy-4'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(piperazin-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C36H41FN6O3S
    N-((1s,4s)-4-(5-fluoro-2-(4'-(3-(piperazin-1-yl)propyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-isopropylthiazole-5-carboxamide —— C36H40FN5O5S
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-isopropylthiazole-5-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C36H41FN6O3S
    N-((1s,4s)-4-(5-fluoro-2-(4'-((4-methyl-1,4-diazepan-1-yl)methyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-isopropylthiazole-4-carboxamide —— C36H40FN5O5S
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-isopropylthiazole-4-carboxamide
    —— N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide —— C34H36FN5O5S
    N-((1s,4s)-4-(5-fluoro-2-(4'-hydroxy-2'-(morpholinomethyl)biphenyl-3-yloxy)nicotinamido)cyclohexyl)-2-methylthiazole-4-carboxamide
    —— 3-(3'-(5-fluoro-3-((1s,4s)-4-(5-methylimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)biphenyl-4-yl)propyl methanesulfonate —— C37H38FN5O6S
    3-(3'-(5-fluoro-3-((1s,4s)-4-(5-methylimidazo[1,2-a]pyridine-2-carboxamido)cyclohexylcarbamoyl)pyridin-2-yloxy)biphenyl-4-yl)propyl methanesulfonate