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    首页 分子通 按分子结构分类 有机化合物 生物碱及其衍生物 原小檗碱生物碱及其衍生物

    原小檗碱生物碱及其衍生物

    中文名称 英文名称 CAS号 化学式 结构式图片
    —— (13S,13aR)-N-(1,3-benzodioxol-5-yl)-2,3-diethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C29H28N2O6
    (13S,13aR)-N-(1,3-benzodioxol-5-yl)-2,3-diethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-2,3-diethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C27H33N3O4
    (13R,13aR)-2,3-diethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-2,3-dimethoxy-N-(2-methyl-3-nitrophenyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H25N3O6
    (13R,13aS)-2,3-dimethoxy-N-(2-methyl-3-nitrophenyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-N-(3,3-diethoxypropyl)-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H34N2O6
    (13R,13aS)-N-(3,3-diethoxypropyl)-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-13-(4-ethylpiperazine-1-carbonyl)-2,3-dimethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C26H31N3O4
    (13S,13aR)-13-(4-ethylpiperazine-1-carbonyl)-2,3-dimethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aS)-N-(3,3-diethoxypropyl)-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H34N2O6
    (13S,13aS)-N-(3,3-diethoxypropyl)-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aS)-2,3-dimethoxy-N-[3-(4-methylpiperazin-1-yl)propyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H36N4O4
    (13S,13aS)-2,3-dimethoxy-N-[3-(4-methylpiperazin-1-yl)propyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C25H29N3O4
    (13R,13aR)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-8-oxo-N-[3-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13S,13aR)-8-oxo-N-[3-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-2,3-dimethoxy-13-[(3R)-3-methylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C26H30N2O4
    (13S,13aR)-2,3-dimethoxy-13-[(3R)-3-methylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C25H29N3O4
    (13R,13aS)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-13-(4-benzylpiperazine-1-carbonyl)-2,3-dimethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C31H33N3O4
    (13S,13aR)-13-(4-benzylpiperazine-1-carbonyl)-2,3-dimethoxy-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-2,3-dimethoxy-N-(2-morpholin-4-ylethyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C26H31N3O5
    (13S,13aR)-2,3-dimethoxy-N-(2-morpholin-4-ylethyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C25H29N3O4
    (13S,13aR)-2,3-dimethoxy-13-(4-methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13S,13aR)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-2,3-dimethoxy-N-(2-morpholin-4-ylethyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C26H31N3O5
    (13R,13aS)-2,3-dimethoxy-N-(2-morpholin-4-ylethyl)-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-2,3-dimethoxy-13-[(3R)-3-methylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C26H30N2O4
    (13R,13aR)-2,3-dimethoxy-13-[(3R)-3-methylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aS)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C28H33N3O2
    (13S,13aS)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aR)-13-(4-benzylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C29H29N3O2
    (13R,13aR)-13-(4-benzylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-8-oxo-N-[3-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13R,13aS)-8-oxo-N-[3-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C28H33N3O2
    (13R,13aR)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-N-[(1R,2S,3R)-2,3-dimethylcyclohexyl]-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H34N2O4
    (13R,13aS)-N-[(1R,2S,3R)-2,3-dimethylcyclohexyl]-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13R,13aS)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aS)-13-[(3R,5R)-3,5-dimethylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C25H28N2O2
    (13S,13aS)-13-[(3R,5R)-3,5-dimethylpiperidine-1-carbonyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aS)-13-(4-benzylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C29H29N3O2
    (13S,13aS)-13-(4-benzylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C24H27N3O2
    (13R,13aS)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C24H27N3O2
    (13S,13aR)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aS)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13S,13aS)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C28H33N3O2
    (13S,13aR)-13-(4-cyclohexylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aR)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C24H27N3O2
    (13R,13aR)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aS)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C24H27N3O2
    (13S,13aS)-13-(4-ethylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aR)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C25H19F3N2O2
    (13R,13aR)-8-oxo-N-[4-(trifluoromethyl)phenyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— 13-(4-Methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C23H25N3O2
    13-(4-Methylpiperazine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aR)-N-[(2-ethoxyphenyl)methyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H26N2O3
    (13R,13aR)-N-[(2-ethoxyphenyl)methyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-10,11-dimethoxy-8-oxo-N-[3-(2-oxopyrrolidin-1-yl)propyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H31N3O5
    (13S,13aR)-10,11-dimethoxy-8-oxo-N-[3-(2-oxopyrrolidin-1-yl)propyl]-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-N-(1-benzylpiperidin-4-yl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C32H35N3O4
    (13R,13aS)-N-(1-benzylpiperidin-4-yl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aS)-N-[2-(4-benzylpiperazin-1-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C31H34N4O2
    (13S,13aS)-N-[2-(4-benzylpiperazin-1-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-N-(2-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H28N2O4
    (13S,13aR)-N-(2-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-N-[(1S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H26N2O4
    (13R,13aS)-N-[(1S)-1-(2,3-dihydro-1,4-benzodioxin-6-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-N-(3-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H28N2O4
    (13S,13aR)-N-(3-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-N-[[1-[(3-methylphenyl)methyl]piperidin-4-yl]methyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C32H35N3O2
    (13R,13aS)-N-[[1-[(3-methylphenyl)methyl]piperidin-4-yl]methyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-N-[(4-ethylphenyl)methyl]-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C29H30N2O4
    (13R,13aR)-N-[(4-ethylphenyl)methyl]-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-N-[2-(4-benzylpiperazin-1-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C31H34N4O2
    (13R,13aR)-N-[2-(4-benzylpiperazin-1-yl)ethyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aR)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C30H37N3O4
    (13R,13aR)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13S,13aR)-N-[3-(4-benzylpiperazin-1-yl)propyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C32H36N4O2
    (13S,13aR)-N-[3-(4-benzylpiperazin-1-yl)propyl]-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aS)-N-(3-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C28H28N2O4
    (13S,13aS)-N-(3-ethylphenyl)-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13S,13aR)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C30H37N3O4
    (13S,13aR)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one —— C30H37N3O4
    (13R,13aS)-10,11-dimethoxy-13-(4-piperidin-1-ylpiperidine-1-carbonyl)-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinolin-8-one
    —— (13R,13aS)-N-[(2-chlorophenyl)methyl]-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C27H25ClN2O4
    (13R,13aS)-N-[(2-chlorophenyl)methyl]-2,3-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide
    —— (13R,13aS)-N-[(2-ethoxyphenyl)methyl]-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide —— C29H30N2O5
    (13R,13aS)-N-[(2-ethoxyphenyl)methyl]-10,11-dimethoxy-8-oxo-5,6,13,13a-tetrahydroisoquinolino[2,1-b]isoquinoline-13-carboxamide