吡咯并三嗪类
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | 4-[(2S)-2-[5-chloro-4-oxo-3-(pyridin-3-ylmethyl)pyrrolo[2,1-f][1,2,4]triazin-2-yl]azetidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | 1548333-83-0 | C22H16ClN9O |
| —— | methyl 2-(3-nitrophenyl)-4-oxo-3,4-dihydropyrrolo[2,1-f][1,2,4]triazine-6-carboxylate | 1427157-94-5 | C14H10N4O5 |
| —— | 4-amino-N-(trans-4-hydroxycyclohexyl)-7-(4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide | 1338049-20-9 | C18H20N6O2 |
| —— | 4-[(2S,4R)-2-(5-chloro-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)-4-fluoropyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | 1548333-30-7 | C23H16ClFN8O |
| —— | 5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-7-[[(2-methyl-2-morpholin-4-ylpropyl)amino]methyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine | 1451252-09-7 | C25H32N6O2S |
| —— | 4-[(2S)-2-(5-chloro-3-cyclobutyl-4-oxopyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | 1548338-01-7 | C21H19ClN8O |
| —— | 5-chloro-2-[(2S)-1-(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)azetidin-2-yl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1548337-47-8 | C21H15ClFN7O |
| —— | 4-hydroxy-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-propanoic acid methyl ester | 310452-44-9 | C11H13N3O3 |
| —— | 4-[(2S)-2-[5-chloro-3-(2-methylpropyl)-4-oxopyrrolo[2,1-f][1,2,4]triazin-2-yl]pyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | 1548333-94-3 | C21H21ClN8O |
| —— | (3R)-1-[[4-amino-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]methyl]pyrrolidin-3-ol | 1451252-18-8 | C21H23N5O2S |
| —— | 2-[(2S)-1-(6-amino-5-chloropyrimidin-4-yl)pyrrolidin-2-yl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1548332-11-1 | C20H18ClN7O |
| —— | 5-chloro-3-phenyl-2-[(2S)-1-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl]pyrrolo[2,1-f][1,2,4]triazin-4-one | 1548337-33-2 | C22H18ClN7O |
| —— | (3R,4R)-4-amino-1-[[4-[(3-methoxyphenyl)amino]pyrrolo[2,1-f][1,2,4]triazin-5-yl]methyl]piperidin-3-ol hydrochloride | 946049-48-5 | C19H24N6O2*ClH |
| —— | 2-(2-((2-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)ethoxy)ethanol | 1026146-25-7 | C16H21N7O2 |
| —— | (2S)-1-((2-((5-cyclopropyl-1H-pyrazol-3-yl)amino)pyrrolo[2,1-f][1,2,4]triazin-4-yl)amino)-2-propanol | 1026146-39-3 | C15H19N7O |
| —— | 5-fluoro-2-[(2S)-1-(5-methylsulfinyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1549737-97-4 | C23H20FN7O2S |
| —— | 4-[(2S)-2-(5-chloro-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)azetidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carboxamide | 1548338-05-1 | C22H17ClN8O2 |
| —— | tert-butyl (trans-4-(((4-amino-7-(4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazin-5-yl)carbonyl)amino)cyclohexyl)carbamate | 1338049-26-5 | C23H29N7O3 |
| —— | 2-[(2S)-1-(5-acetyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl]-5-chloro-3-(4-fluorophenyl)pyrrolo[2,1-f][1,2,4]triazin-4-one | 1549737-23-6 | C24H19ClFN7O2 |
| —— | 2-[(2S)-1-(6-amino-5-chloropyrimidin-4-yl)pyrrolidin-2-yl]-5-chloro-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1548332-58-6 | C20H17Cl2N7O |
| —— | 6-(hydroxy(phenyl)methyl)-5-methylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one | 1401623-41-3 | C14H13N3O2 |
| —— | 5-chloro-2-[(2S)-1-(5-fluoro-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1548337-44-5 | C22H17ClFN7O |
| —— | (S)-2-(1-(6-amino-5-iodopyrimidin-4-ylamino)ethyl)-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one | 1605328-62-8 | C18H16IN7O |
| —— | 7-(2-Aminobutoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | 1451252-46-2 | C21H25N5O2S |
| —— | (S)-tert-butyl 1-(4-oxo-3-phenyl-5-(trifluoromethyl)-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)ethylcarbamate | 1403942-76-6 | C20H21F3N4O3 |
| —— | (S)-3-phenyl-2-(1-(7-((2-(trimethylsilyl)ethoxy)methyl)-5-vinyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl)pyrrolo[1,2-f][1,2,4]triazin-4(3H)-one | 1548341-23-6 | C30H35N7O2Si |
| —— | 2-[(2S)-1-(2-amino-7H-pyrrolo[2,3-d]pyrimidin-4-yl)pyrrolidin-2-yl]-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4-one | 1548331-79-8 | C22H20N8O |
| —— | 4-amino-6-[(2S)-2-(5-bromo-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)azetidin-1-yl]pyrimidine-5-carbonitrile | 1549736-31-3 | C20H15BrN8O |
| —— | 4-[(2S)-2-(5-cyclopropyl-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl)pyrrolidin-1-yl]-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile | 1548333-47-6 | C26H22N8O |
| —— | US9598416, Example 52 | 1443617-11-5 | C23H27N5O2S |
| —— | 4-chloro-5-methylpyrrolo[2,1-f][1,2,4]triazine-6-propanoic acid methyl ester | 310444-89-4 | C11H12ClN3O2 |
| —— | 1-[4-Amino-6-(ethoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazine-7-carbonyl]imidazolidin-4-one | 1443531-45-0 | C23H24N6O4S |
| —— | methyl 2-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)cyclopent-1-enecarboxylate | 1072811-76-7 | C19H20N6O2 |
| —— | US9598416, Example 43 | 1443617-02-4 | C23H27N5O2S |
| —— | 2-[3-[2-[1-(5-Bromopyrimidin-2-yl)-4-morpholin-4-ylpiperidin-4-yl]ethoxy]-4-chlorophenyl]acetic acid | 928023-35-2 | C23H28BrClN4O4 |
| —— | 7-(2-Aminopropoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | 1451252-53-1 | C20H23N5O2S |
| —— | 3-[5-nitro-4-(tetrahydro-2H-pyran-4-ylamino)pyrimidin-2-yl]pyrazolo[1,5-a]pyridine-5-carbonitrile | 1299420-52-2 | C17H15N7O3 |
| —— | 4-amino-6-[(2S)-2-[5-(methoxymethyl)-4-oxo-3-phenylpyrrolo[2,1-f][1,2,4]triazin-2-yl]pyrrolidin-1-yl]pyrimidine-5-carbonitrile | 1549736-37-9 | C23H22N8O2 |
| —— | 5-(7-Methoxy-5-methyl-1-benzothiophen-2-yl)-7-(oxolan-3-yloxymethyl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | 1451252-47-3 | C21H22N4O3S |
| —— | [4-Amino-6-(ethoxymethyl)-5-(7-methoxy-5-methyl-1-benzothiophen-2-yl)pyrrolo[2,1-f][1,2,4]triazin-7-yl]-(1,1-dioxo-1,4-thiazinan-4-yl)methanone | 1443531-53-0 | C24H27N5O5S2 |
| —— | 2-(difluoro(4-fluorophenyl)methyl)-4-(5-methyl-1H-pyrazol-3-ylamino)pyrrolo[2,1-f][1,2,4]triazine-6-carboxylic acid | 1204245-42-0 | C18H13F3N6O2 |
| —— | 2-(hydroxymethyl)-5-methyl-3-phenylpyrrolo[2,1-f][1,2,4]triazin-4(3H)-one | 1604801-83-3 | C14H13N3O2 |
| —— | (2R,3R,4R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-1,3,4-tris(phenylmethoxy)hept-6-yne-2,5-diol | 1355050-15-5 | C34H34N4O5 |
| —— | 4-chloropyrrolo[2,1-f][1,2,4]triazine-5-carbaldehyde | 859854-70-9 | C7H4ClN3O |
| —— | (R)-2-(1-amino-2-hydroxyethyl)-3-(3,5-difluorophenyl)-4-oxo-3,4-dihydropyrrolo[1,2-f][1,2,4]triazine-5-carbonitrile | 1403943-37-2 | C15H11F2N5O2 |
| —— | 6-bromo-5,8-diphenyl-2H-pyrazolo[1,5-c]-1,2,4-triazolo[4,3-a]pyrimidine-3-thione | 1338219-14-9 | C19H12BrN5S |
| —— | (S)-tert-butyl 1-(5-iodo-4-oxo-3-(pyridin-2-ylmethyl)-3,4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)ethylcarbamate | 1403943-53-2 | C19H22IN5O3 |
| —— | (S)-tert-butyl 1-(5-bromo-4-oxo-3-(pyridin2-ylmethyl)-3.4-dihydropyrrolo[1,2-f][1,2,4]triazin-2-yl)ethylcarbamate | 1403943-52-1 | C19H22BrN5O3 |
| —— | US9598416, Example 54 | 1443617-13-7 | C22H25N5O2S |
| —— | 4-amino-N-(3-(methylamino)propyl)-7-(4-pyridinyl)pyrrolo[2,1-f][1,2,4]triazine-5-carboxamide | 1338049-15-2 | C16H19N7O |
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