以NADH或NADPH作为一个供体，并将两个氧原子并入另一个供体
| 中文名称 | 英文名称 | CAS号 | 化学式 |
|---|---|---|---|
| —— | 4-sulfobenzoate 3,4-dioxygenase | 122933-81-7 | —— |
| —— | p-cumate 2,3-dioxygenase | —— | —— |
| —— | biphenyl 2,3-dioxygenase | 103289-55-0 | —— |
| —— | chlorobenzene dioxygenase | —— | —— |
| —— | 3-phenylpropanoate dioxygenase | 105503-66-0 | —— |
| —— | nitric oxide dioxygenase | 214466-78-1 | —— |
| —— | carbazole 1,9a-dioxygenase | 194812-10-7 | —— |
| —— | nitroarene dioxygenase | —— | —— |
| —— | 2-aminobenzenesulfonate 2,3-dioxygenase | 156621-16-8 | —— |
| —— | 2,4-dinitrotoluene dioxygenase | —— | —— |
| —— | terephthalate 1,2-dioxygenase | 162032-76-0 | —— |
| —— | benzoate 1,2-dioxygenase | 9059-18-1 | —— |
| —— | 2-hydroxyquinoline 5,6-dioxygenase | 172399-50-7 | —— |
| —— | 2-halobenzoate 1,2-dioxygenase | 125268-83-9 | —— |
| —— | naphthalene 1,2-dioxygenase | 9074-04-8 | —— |
| —— | 4-chlorophenylacetate 3,4-dioxygenase | 105006-00-6 | —— |
| —— | phthalate 4,5-dioxygenase | 63626-44-8 | —— |
| —— | benzene 1,2-dioxygenase | 9075-66-5 | —— |
| —— | anthranilate 1,2-dioxygenase (deaminating, decarboxylating) | 9059-17-0 | —— |
| —— | toluene dioxygenase | 120038-36-0 | —— |
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