5-Fluor-2-butoxy-benzaldehyd | 19415-56-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 5-Fluor-2-butoxy-benzaldehyd
• 英文别名: 2-Butoxy-5-fluorobenzaldehyde
• CAS: 19415-56-6
• 化学式: C₁₁H₁₃FO₂
• 分子量: 196.221
• InChiKey: KKESHXOGWVVWNR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.7
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  5-Fluor-2-butoxy-α-chlortoluol 在 乌洛托品 作用下， 以 氯仿 为溶剂， 生成 5-Fluor-2-butoxy-benzaldehyd
  参考文献：
  名称：

  Maziere,B.; Dat-Xuong,N., Chimica Therapeutica, 1968, vol. 3, p. 1 - 9

  摘要：

  DOI：

文献信息

• [EN] ACC INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS DE L'ACC ET UTILISATIONS ASSOCIÉES
  申请人：GILEAD APOLLO LLC

  公开号：WO2017075056A1

  公开（公告）日：2017-05-04

  The present invention provides compounds I and II useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.

  本发明提供了化合物I和II，这些化合物可用作乙酰辅酶A羧化酶（ACC）的抑制剂，以及它们的组合物和使用方法。
• TRIAZOLE ACC INHIBITORS AND USES THEREOF
  申请人：Gilead Apollo, LLC

  公开号：US20170166584A1

  公开（公告）日：2017-06-15

  The present invention provides triazole compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.

  本发明提供了三唑化合物，可用作乙酰辅酶A羧化酶（ACC）的抑制剂，以及其组合物和使用方法。
• Sulfamate Derivative Compounds for Use in Treating or Alleviating Pain
  申请人：BIO-PHARM SOLUTIONS CO., LTD.

  公开号：US20160311792A1

  公开（公告）日：2016-10-27

  The present invention relates to sulfamate derivative compounds and a composition for treating and/or alleviating pain containing the sulfamate derivative compounds or a pharmaceutically acceptable salt thereof as an active ingredient. More specifically the present invention relates to a pharmaceutical composition for treating or alleviating pain containing a sulfamate derivative compound and/or a pharmaceutically acceptable salt thereof as an active ingredient. Furthermore, the present invention relates to a method for treatment or alleviation of pain comprising administering a sulfamate derivative compound in a pharmaceutically effective amount to a subject in need of treatment or alleviation of pain.
• ACC INHIBITORS AND USES THEREOF
  申请人：Gilead Apollo, LLC

  公开号：US20170145028A1

  公开（公告）日：2017-05-25

  The present invention provides compounds useful as inhibitors of Acetyl CoA Carboxylase (ACC), compositions thereof, and methods of using the same.
• [EN] TRIAZOLE ACC INHIBITORS AND USES THEREOF<br/>[FR] INHIBITEURS D'ACC À BASE DE TRIAZOLE ET UTILISATIONS ASSOCIÉES
  申请人：GILEAD APOLLO LLC

  公开号：WO2017091617A1

  公开（公告）日：2017-06-01

  The invention provides triazole compounds of formula (I) inhibiting Acetyl CoA Carboxylase (ACC), compositions and uses thereof for the treatment of obesity or as fungicides.