N(b),21-Dihydro-talpinin | 38990-07-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 大灵碱生物碱
• 英文名称: N(b),21-Dihydro-talpinin
• 英文别名: 21β-methyl-(20βH)-20,21-dihydro-19,23-dinor-alstophyllan-18-ol；(19S,20S)-17,19-epoxy-1-methyl-19,20-dihydro-4,21-seco-sarpagan-21-ol
• CAS: 38990-07-7
• 化学式: C₂₀H₂₆N₂O₂
• 分子量: 326.439
• InChiKey: BXYUQBYZSFOVMX-KNFFYRPMSA-N

物化性质

• 沸点：
  534.8±50.0 °C(Predicted)
• 密度：
  1.42±0.1 g/cm3(Predicted)

反应信息

• 作为反应物：
  描述：

  N(b),21-Dihydro-talpinin 、 乙酸酐 生成 N-Monoacetyl-N(b),21-dihydro-talpinin
  参考文献：
  名称：

  Über die Indolalkaloide vonPleiocarpa talbotiiWernham. 145. Mitteilung über Alkaloide

  摘要：

  AbstractBesides talbotine (1) three new indole alkaloids, talpinine (2), talcarpine (3) and 16‐epi‐affinine (4) were isolated from the stem bark of Pleiocarpa talbotii Wernham. The structure of 2 was deduced by chemical degradation and by analyses of the spectra of the alkaloid and its derivatives. One of these derivatives is identical with talcarpine (3).The structures 2 and 3 are similar to that of macroline (14), a splitting product of the bisindole alkaloid villalstonine from Alstonia species. 16‐epi‐Affinine (4) was chemically correlated with the known alkaloid vobasine (19).Talpinine (2) and 16‐epi‐affinine (4) were also isolated from the root bark of Pleiocarpa talbotii.

  DOI：

  10.1002/hlca.19720550304
• 作为产物：
  描述：

  Talpinin 在 sodium tetrahydroborate 作用下， 生成 N(b),21-Dihydro-talpinin
  参考文献：
  名称：

  Über die Indolalkaloide vonPleiocarpa talbotiiWernham. 145. Mitteilung über Alkaloide

  摘要：

  AbstractBesides talbotine (1) three new indole alkaloids, talpinine (2), talcarpine (3) and 16‐epi‐affinine (4) were isolated from the stem bark of Pleiocarpa talbotii Wernham. The structure of 2 was deduced by chemical degradation and by analyses of the spectra of the alkaloid and its derivatives. One of these derivatives is identical with talcarpine (3).The structures 2 and 3 are similar to that of macroline (14), a splitting product of the bisindole alkaloid villalstonine from Alstonia species. 16‐epi‐Affinine (4) was chemically correlated with the known alkaloid vobasine (19).Talpinine (2) and 16‐epi‐affinine (4) were also isolated from the root bark of Pleiocarpa talbotii.

  DOI：

  10.1002/hlca.19720550304