| 153941-17-4

• 分子结构分类: 有机化合物
• CAS: 153941-17-4
• 化学式: C₁₂H₂₆N₃P
• 分子量: 243.332
• InChiKey: RDWWVRJFFJIQEZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.81
• 重原子数：
  16.0
• 可旋转键数：
  4.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.92
• 拓扑面积：
  39.64
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  在 1,2,3,4,5,6,7,8-八硫杂环辛烷 作用下， 以 甲苯 为溶剂， 反应 24.0h， 以74%的产率得到
  参考文献：
  名称：

  Diazoverbindungen. 72. (Diazoalkyl)phosphane - Synthese durch elektrophile Diazoalkansubstitution und oxidative Additionsreaktionen am Phosphor

  摘要：

  Electrophilic diazoalkane substitution of the diazomethyl compounds lab with the chloro phosphanes 2a-o in the presence of lithium diethylamide yields the diazoalkyl phosphanes 3a-z. Oxidative addition of oxygen, sulfur and selenium at phosphorus leads into the series of oxo, thioxo and selenoxo phosphanes having diazoalkyl substituents (4a-d, 5a-m and 7a-d). The silyl group of 5n,o is cleaved by chromatography on aluminium oxide to yield the (diazomethyl)phosphane sulfides 6a,b.

  DOI：

  10.1002/prac.19933350704
• 作为产物：
  描述：

  1-diazo-2,2-dimethylpropane 、 chloro-N,N-diisopropylaminomethylphosphine 在 lithium diisopropyl amide 作用下， 生成
  参考文献：
  名称：

  Diazoverbindungen. 72. (Diazoalkyl)phosphane - Synthese durch elektrophile Diazoalkansubstitution und oxidative Additionsreaktionen am Phosphor

  摘要：

  Electrophilic diazoalkane substitution of the diazomethyl compounds lab with the chloro phosphanes 2a-o in the presence of lithium diethylamide yields the diazoalkyl phosphanes 3a-z. Oxidative addition of oxygen, sulfur and selenium at phosphorus leads into the series of oxo, thioxo and selenoxo phosphanes having diazoalkyl substituents (4a-d, 5a-m and 7a-d). The silyl group of 5n,o is cleaved by chromatography on aluminium oxide to yield the (diazomethyl)phosphane sulfides 6a,b.

  DOI：

  10.1002/prac.19933350704