| 1158537-33-7

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 四吡咯及其衍生物
• CAS: 1158537-33-7
• 化学式: C₁₅₂H₁₉₂N₈O₁₆Zn
• 分子量: 2452.63
• InChiKey: QKFXBAWNFXTQIN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  在 乙硫醇钠 、 水 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 24.0h， 以25%的产率得到ZINC;2,5-ditert-butyl-4-[[7,15,16,24,25,33,34-heptakis(2,5-ditert-butyl-4-hydroxyphenoxy)-2,11,20,29,37,39-hexaza-38,40-diazanidanonacyclo[28.6.1.13,10.112,19.121,28.04,9.013,18.022,27.031,36]tetraconta-1,3,5,7,9,11,13,15,17,19(39),20,22,24,26,28,30(37),31,33,35-nonadecaen-6-yl]oxy]phenol
  参考文献：
  名称：

  Syntheses and properties of octa-, tetra-, and di-hydroxy-substituted phthalocyanines

  摘要：

  The synthesis and photophysical properties of a new series of zinc(II) phthalocyanines (ZnPcs) bearing multiple hydroxy and tert-butyl groups are reported. The X-ray structures of two phthalonitriles and one ZnPc are presented. All hydroxy-substituted ZnPcs show low fluorescence quantum yields in DMSO and complete fluorescence quenching in aqueous solutions, but high singlet oxygen quantum yields in DMSO (0.2-0.7). Our results suggest that the tetra- and octa-hydroxy ZnPcs might find application as photosensitizers in the PDT treatment of cancer. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.012
• 作为产物：
  描述：

  C₁₅₂H₁₉₄N₈O₁₆ 在 zinc diacetate 作用下， 以 戊醇 为溶剂， 反应 3.0h， 以0.12 g的产率得到
  参考文献：
  名称：

  Syntheses and properties of octa-, tetra-, and di-hydroxy-substituted phthalocyanines

  摘要：

  The synthesis and photophysical properties of a new series of zinc(II) phthalocyanines (ZnPcs) bearing multiple hydroxy and tert-butyl groups are reported. The X-ray structures of two phthalonitriles and one ZnPc are presented. All hydroxy-substituted ZnPcs show low fluorescence quantum yields in DMSO and complete fluorescence quenching in aqueous solutions, but high singlet oxygen quantum yields in DMSO (0.2-0.7). Our results suggest that the tetra- and octa-hydroxy ZnPcs might find application as photosensitizers in the PDT treatment of cancer. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.02.012