1-(3-((tert-butyldimethylsilyl)oxy)propyl)quinolin-1-ium bromide | 1617001-61-2

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 喹啉及其衍生物
• 英文名称: 1-(3-((tert-butyldimethylsilyl)oxy)propyl)quinolin-1-ium bromide
• CAS: 1617001-61-2
• 化学式: Br*C₁₈H₂₈NOSi
• 分子量: 382.416
• InChiKey: VIQBRBVABKMBDD-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  1.54
• 重原子数：
  22.0
• 可旋转键数：
  5.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  13.11
• 氢给体数：
  0.0
• 氢受体数：
  1.0

反应信息

• 作为反应物：
  描述：

  iodo(5,10,15,20-tetraphenylporphyrinato-κ4N)rhodium(III) 、 1-(3-((tert-butyldimethylsilyl)oxy)propyl)quinolin-1-ium bromide 在 sodium hydroxide 作用下， 以 水 、 苯 为溶剂， 反应 5.0h， 以84%的产率得到[Rh(5,10,15,20-tetraphenylporphyrinato)(CH2CH2CH2OTBS)]
  参考文献：
  名称：

  Alkylation of Rhodium Porphyrins Using Ammonium and Quinolinium Salts

  摘要：

  Alkylation of rhodium(III) porphyrins [Rh-II(por)] was achieved under relatively mild conditions in up to 98% yields, where readily available ammonium and quinolinium salts were utilized as the alkylating agents. This transformation tolerates air and water, thus serving as a convenient method to prepare a variety of alkyl- and benzyl-Rh-III(por) complexes. Preliminary mechanistic studies support an S(N)2-like reaction pathway involving a Rh-I(por) anion intermediate.

  DOI：

  10.1021/om500438s
• 作为产物：
  描述：

  喹啉 、 (3-溴丙氧基)叔丁基二甲基硅烷 在 air 作用下， 反应 2.0h， 生成 1-(3-((tert-butyldimethylsilyl)oxy)propyl)quinolin-1-ium bromide
  参考文献：
  名称：

  Alkylation of Rhodium Porphyrins Using Ammonium and Quinolinium Salts

  摘要：

  Alkylation of rhodium(III) porphyrins [Rh-II(por)] was achieved under relatively mild conditions in up to 98% yields, where readily available ammonium and quinolinium salts were utilized as the alkylating agents. This transformation tolerates air and water, thus serving as a convenient method to prepare a variety of alkyl- and benzyl-Rh-III(por) complexes. Preliminary mechanistic studies support an S(N)2-like reaction pathway involving a Rh-I(por) anion intermediate.

  DOI：

  10.1021/om500438s