i-PrC2(B10H10)CH(COOH)Ph | 145826-09-1

• 英文名称: i-PrC2(B10H10)CH(COOH)Ph
• CAS: 145826-09-1
• 化学式: C₁₃H₂₄B₁₀O₂
• 分子量: 320.442
• InChiKey: XTNRBGRECMIHSX-SNVBAGLBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  None
• 重原子数：
  None
• 可旋转键数：
  None
• 环数：
  None
• sp3杂化的碳原子比例：
  None
• 拓扑面积：
  None
• 氢给体数：
  None
• 氢受体数：
  None

反应信息

• 作为反应物：
  描述：

  i-PrC2(B10H10)CH(COOH)Ph 、 lithium aluminium tetrahydride 以 乙醚 为溶剂， 生成 i-PrC2(B10H10)CH(CH2OH)Ph
  参考文献：
  名称：

  Metallization of 1-substituted 1-benzyl-o-carboranes with n-butyllithium and some conversions of 1-R-2-benzyllithium-o-carboranes

  摘要：

  It was shown that 1-R-2-benzyl-o-carboranes (R = Me, i-Pr, Ph, PhCH2) and other derivatives of o-carborane containing an ArCH2 group in positions 1 and 2 are readily metallized by n-butyllithium, forming the corresponding benzyllithium derivatives, which react with electrophilic reagents like the usual organolithium compounds, permitting the synthesis of various C-substituted 1-o-carboranes.

  DOI：

  10.1007/bf00869528
• 作为产物：
  描述：

  1-i-propyl-2-benzyllithium-o-carborane 、 二氧化碳 以85%的产率得到i-PrC2(B10H10)CH(COOH)Ph
  参考文献：
  名称：

  Metallization of 1-substituted 1-benzyl-o-carboranes with n-butyllithium and some conversions of 1-R-2-benzyllithium-o-carboranes

  摘要：

  It was shown that 1-R-2-benzyl-o-carboranes (R = Me, i-Pr, Ph, PhCH2) and other derivatives of o-carborane containing an ArCH2 group in positions 1 and 2 are readily metallized by n-butyllithium, forming the corresponding benzyllithium derivatives, which react with electrophilic reagents like the usual organolithium compounds, permitting the synthesis of various C-substituted 1-o-carboranes.

  DOI：

  10.1007/bf00869528

文献信息

• Synthesis of the first stable carborane containing simple enol
  作者：L. I. Zakharkin、V. A. Ol'shevskaya、G. G. Zhigareva

  DOI：10.1007/bf01434241

  日期：1996.6

  A carborane-containing stable simple enol — 1-2-isopropyl-o-carboran-I-yl)-1-phenyl2-mesityl-2-lrydroxyctlrylcne — has been synthesized. This enol does not isomerize to the starting ketone or keto-enol mixture even after prolonged heating in benzene in the presence of CF3COOH.

  已合成含碳硼烷的稳定简单烯醇 - 1-2-异丙基-o-carboran-I-yl)-1-phenyl2-mesityl-2-lrydroxyctlrylcne。即使在 CF3COOH 存在下在苯中长时间加热后，该烯醇也不会异构化为起始酮或酮-烯醇混合物。