| 1182838-60-3

• 分子结构分类: 有机化合物 - 有机氧化合物
• CAS: 1182838-60-3
• 化学式: C₆H₁₄N₂O₂*C₁₀₂H₁₇₂N₄O₇₆
• 分子量: 2816.66
• InChiKey: CJPNAVOWTIPFBV-JUUACVSZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -31.3
• 重原子数：
  192.0
• 可旋转键数：
  23.0
• 环数：
  43.0
• sp3杂化的碳原子比例：
  0.97
• 拓扑面积：
  1299.04
• 氢给体数：
  47.0
• 氢受体数：
  79.0

反应信息

• 作为产物：
  描述：

  (2R,11R,19R,21R)-2,11-bis(1-hydroxyethyl)-1,10-N,N'-bis[cyclomaltoheptaosyl-6^A-deoxy-6^A-ureido]-4,7,13,16-tetraoxa-1,10-diaza-cyclooctadecane 、 L-赖氨酸 以 水 为溶剂， 反应 18.0h， 生成
  参考文献：
  名称：

  Bis-β-cyclodextrinyl- and bis-cellobiosyl-diazacrowns: synthesis and molecular complexation behaviors toward Busulfan anticancer agent and two basic aminoacids

  摘要：

  The one-step synthesis of two C-2-symmetric receptors including two beta-cyclodextrin cores or two disaccharidyl units connected by urea linkers to a diazacrown ether organizing platform is reported. The X-ray structure of the peracetylated bis-ureidocellobiosyl podand could be determined. These molecular systems, long thought to be potent selective carriers for chiral/achiral organic guests at the supramolecular level, were found to be efficient complexing tools toward the Busulfan anticancer agent but also toward L-arginine and L-lysine basic aminoacids. (C) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.05.057