| 1610628-78-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二氮杂萘
• CAS: 1610628-78-8
• 化学式: C₁₇H₂₀N₂O₂
• 分子量: 284.358
• InChiKey: BFVUTJQLUDATPR-UHFFFAOYSA-N

反应信息

• 作为产物：
  描述：

  、 邻苯二胺 在 对甲苯磺酸 作用下， 反应 1.0h， 生成
  参考文献：
  名称：

  DDQ-mediated oxidation of sp3 C–H bond for the direct synthesis of vicinal tricarbonyl compounds

  摘要：

  A facile and direct synthetic method was developed for the construction of vicinal tricarbonyl compounds (VTCs) in moderate to excellent yields (46-92%), by treating the readily available 1,3-dicarbonyl compounds with 2,2,6,6-tetramethylpiperidine-1-oxyl (TEMPO) in the presence of 2,3-dichloro-5,6-dicyano-1,4-benzoquinone (DDQ). The reaction pathway involves the DDQ-mediated oxidative activation of sp(3) C-H bond and subsequent coupling to TEMPO to form the key intermediate TEMPO-substrate adduct, which can be further converted to VTC products promoted by DDQ (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2014.04.021