2,3,3,N-Tetramethyl-butyramide | 58265-29-5

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,3,3,N-Tetramethyl-butyramide
• 英文别名: N,2,3,3-tetramethylbutanamide
• CAS: 58265-29-5
• 化学式: C₈H₁₇NO
• mdl: MFCD03413076
• 分子量: 143.229
• InChiKey: MUIXFXJEUCWKKY-UHFFFAOYSA-N

物化性质

• 熔点：
  85-86 °C
• 沸点：
  213.9±8.0 °C(Predicted)
• 密度：
  0.857±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  10
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.875
• 拓扑面积：
  29.1
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  4-tert-Butyl-3,5-dimethyl-4,5-dihydro-3H-[1,2,3]triazol-4-ol 在 盐酸 作用下， 以 二氯甲烷 为溶剂， 生成 2,3,3,N-Tetramethyl-butyramide
  参考文献：
  名称：

  Olsen,C.E., Acta chemica Scandinavica. Series B: Organic chemistry and biochemistry, 1975, vol. 29, p. 953 - 962

  摘要：

  DOI：

文献信息

• Chain transfer agents for raft polymerization in aqueous media
  申请人：McCormick L. Charles

  公开号：US20070123670A1

  公开（公告）日：2007-05-31

  Polymers and copolymers synthesized by means that yield a narrow range of molecular weights can have different properties than polymers synthesized by conventional means. In order to obtain such polymers, however, polymerization must be controlled. One type of controlled polymerization is the reversible addition-fragmentation chain transfer (RAFT) process, which has characteristics of a living polymerization. The present invention discloses a group of dithioesters and trithioesters suitable as chain transfer agents for RAFT polymerization. The present invention also discloses RAFT polymerizations conducted in aqueous media.

  通过产生分子量窄范围的手段合成的聚合物和共聚物可能具有不同于传统手段合成的聚合物的性质。然而，为了获得这种聚合物，聚合必须受到控制。一种受控聚合的类型是可逆加成-断裂链转移（RAFT）过程，具有活性聚合的特征。本发明揭示了一组二硫代酯和三硫代酯，适用于RAFT聚合的链转移剂。本发明还揭示了在水介质中进行的RAFT聚合。
• NOVEL PYRROLIDINE DERIVED BETA 3 ADRENERGIC RECEPTOR AGONISTS
  申请人：Edmondson Scott D.

  公开号：US20120157432A1

  公开（公告）日：2012-06-21

  The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.

  本发明提供公式（I）的化合物、其制药组合物以及使用该化合物治疗或预防通过激活β3-肾上腺素受体介导的疾病的方法。
• OLSEN C. E., ACTA CHEM. SCAND. <ACSA-A4>, 1975, B29, NO 9, 953-962
  作者：OLSEN C. E.

  DOI：——

  日期：——
• Molecular Chaperone Function Regulator
  申请人：Suzuki Tsuyoshi

  公开号：US20080200433A1

  公开（公告）日：2008-08-21

  According to the present invention, a molecular chaperone function regulator containing a quinazoline derivative represented by the following formula (I) wherein each symbol is as defined in Claims, or a pharmaceutically acceptable salt thereof, a hydrate or solvate thereof, an optically active form or racemate thereof or a diastereomer mixture thereof as an active ingredient can be provided.
• COMPOSITION FOR PENETRATING SUGAR BASED DELIVERY SYSTEM
  申请人：Air Products and Chemicals, Inc.

  公开号：US20170042784A1

  公开（公告）日：2017-02-16

  Water based composition comprising a sugar based delivery system, coemulsifiers and a positively charged molecule, oil, optional auxiliary materials and optional lipophilic active ingredients encapsulated to be used in Personal Care products including Cosmetics. The composition is penetrating into the skin and is, depending on the active included, able to stabilize the substance and reduce its irritation potential.