4-methoxy-toluene-3-sulfinic acid | 743376-73-0

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 4-methoxy-toluene-3-sulfinic acid
• 英文别名: 4-Methoxy-toluol-3-sulfinsaeure；4-Methoxy-1-methyl-benzol-sulfinsaeure-(3)；p-Kresolmethylaether-sulfinsaeure-(2)；2-Methoxy-5-methylbenzene-1-sulfinic acid；2-methoxy-5-methylbenzenesulfinic acid
• CAS: 743376-73-0
• 化学式: C₈H₁₀O₃S
• 分子量: 186.232
• InChiKey: FJDVWGNJOLTMDX-UHFFFAOYSA-N

物化性质

• 沸点：
  403.3±55.0 °C(Predicted)
• 密度：
  1.36±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.5
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  65.7
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4-methoxy-toluene-3-sulfinic acid 在 硫酸 、 二氧化硫 、 氢碘酸 、 溶剂黄146 作用下， 生成 bis-(2-methoxy-5-methyl-phenyl)-disulfide
  参考文献：
  名称：

  Hilditch, Journal of the Chemical Society, 1911, vol. 99, p. 1099

  摘要：

  DOI：
• 作为产物：
  描述：

  对甲苯甲醚 在 二氧化硫 作用下， 生成 4-methoxy-toluene-3-sulfinic acid
  参考文献：
  名称：

  Impact of Ambulance Diversion Policies in Urban, Suburban, and Rural Areas of Central Maryland

  摘要：

  Abstract. As a method to control patient flow to overburdened hospitals, effective emergency medical services (EMS) systems provide policies for ambulance diversion. The Maryland state EMS system supports two types of alert for general hospital use: red alert, aimed at limiting the delivery of patients who may require intensive care unit (ICU) admission, and yellow alert, aimed at preventing further overload of already overtaxed emergency departments (EDs). Objective: To examine the effect of those alert policies in different geographical environments, urban, suburban, and rural. Methods: Alert data for 23 hospitals in Central Maryland and ambulance arrival data for approximately 138,000 ambulance calls during calendar year 1996 were combined and analyzed. The impacts of diversion practices in the geographic areas were compared. Results: Red alert reduced volume in all patient acuity levels in all geographic areas by a statistically significant 0.4 patient/hr. Yellow alert diverted low‐acuity patients at the rate of 0.13 patient/hr (p < 0.001) in urban areas and at the rate of 0.16 patient/hr (p < 0.001) in suburban areas, but had minimal impact in the flow of patients in the rural environment. Conclusions: The ED diversion policy has some limited effect in preventing further patient volume in urban and suburban areas, but has virtually no impact in rural areas. However, an ICU diversion policy diverts patients of all acuities uniformly and inordinately diverts patients not likely to require ICU admissions while having only minimal impact on patients who do require ICU resources. The impact of red alert is uniform in all geographic areas. The impact and efficacy of ambulance diversion policies should be evaluated to ensure they are having the intended effect. While perhaps initially effective, the impact of alert policies may change over time.

  DOI：

  10.1111/j.1553-2712.2001.tb00546.x

文献信息

• Gibson; Smiles, Journal of the Chemical Society, 1923, vol. 123, p. 2390
  作者：Gibson、Smiles

  DOI：——

  日期：——
• Gattermann, Chemische Berichte, 1899, vol. 32, p. 1156
  作者：Gattermann

  DOI：——

  日期：——
• Brooker; Child; Smiles, Journal of the Chemical Society, 1927, p. 1387
  作者：Brooker、Child、Smiles

  DOI：——

  日期：——
• Hilditch; Smiles, Chemische Berichte, 1908, vol. 41, p. 4114
  作者：Hilditch、Smiles

  DOI：——

  日期：——
• Kolhatkar; Bokil, Journal of the Indian Chemical Society, 1930, vol. 7, p. 843
  作者：Kolhatkar、Bokil

  DOI：——

  日期：——