(2-丁氧基-2-丙基)苯 | 54815-20-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: (2-丁氧基-2-丙基)苯
• 英文名称: butyl cumyl ether
• 英文别名: 1-(2-butoxypropan-2-yl)benzene；α-Methyl-α-n-butoxyethylbenzol；butyl-(1-methyl-1-phenyl-ethyl)-ether；Butyl-(1-methyl-1-phenyl-aethyl)-aether；(1-butoxy-1-methylethyl)-benzene；2-Butyloxy-2-phenyl-propan；α-Butyloxy-cumol；(1-Butoxy-1-methylethyl)benzene；2-butoxypropan-2-ylbenzene
• CAS: 54815-20-2
• 化学式: C₁₃H₂₀O
• 分子量: 192.301
• InChiKey: GATSVPFYPIBDAR-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  14
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909309090

反应信息

• 作为反应物：
  描述：

  (2-丁氧基-2-丙基)苯 在 resin Amberlyst 15 (H⁺) 作用下， 生成 正丁醇 、 2-苯基-1-丙烯
  参考文献：
  名称：

  Chemical Equilibria Study of the Reacting System of the Alkyl Cumyl Ether Synthesis from n-Alkanols and α-Methylstyrene

  摘要：

  The chemical equilibrium of the reactive systems n-alkanol + alpha -methylstyrene double left right arrow alkyl cumyl ether (alkyl is ethyl, propyl, and butyl) was studied in the liquid phase in the temperature range (300 to 383) K using a cation exchanger as heterogeneous catalyst. Equilibrium ratios K-x obtained from concentrations of the reaction participants in the mixtures with an excess amount of alkanol are practically independent of the reactive mixture composition and can be identified with the thermodynamic equilibrium; constant K-a. Enthalpies of reactions Delta H-r(m)o of alkyl cumyl ether synthesis in the liquid phase were obtained from the temperature dependence of K-a and showed a good agreement with those reaction enthalpies derived from the values Delta H-f(m)o(l) of the reactions participants measured for alkyl cumyl ethers by combustion calorimetry. The standard molar enthalpies of vaporization of alkyl cumyl ethers were obtained from the temperature dependence of the vapor pressure measured by using the transpiration method. Resulting values of Delta H-f(m)o(g) were used to prove the consistency of the experimental data and to derive strain enthalpies of alkyl cumyl ethers. The strain effects were discussed in terms of deviations of Delta H-f(m)o(g) from the group additivity rules.

  DOI：

  10.1021/je000162a
• 作为产物：
  描述：

  2-苯基-2-丙醇 、 正丁醇 在 nanoporous Au/Ag catalyst 作用下， 以 四氯化碳 、 1,2-二氯乙烷 为溶剂， 生成 (2-丁氧基-2-丙基)苯
  参考文献：
  名称：

  纳米多孔金催化剂对醇的光催化脱水醚化

  摘要：

  纳米多孔金催化剂开发了一种简单有效的醇脱水醚化光催化方法。该协议的特点是无需添加酸或碱、广泛的底物通用性和出色的酸敏感官能团耐受性。机理研究证明了催化体系的多相性，催化剂的可回收性得到反复证明。

  DOI：

  10.1039/d2cc04562a

文献信息

• Selective synthesis of unsymmetrical ethers from different alcohols catalyzed by sodium bisulfite
  作者：Jun-Lai Yu、Hui Wang、Kai-Feng Zou、Jia-Rui Zhang、Xiang Gao、Dan-Wei Zhang、Zhan-Ting Li

  DOI：10.1016/j.tet.2012.10.032

  日期：2013.1

  ethers from alcohols catalyzed by sodium bisulfite is reported. The procedure enables the direct dehydration of primary, secondary, and tertiary benzylic alcohols with aliphatic alcohols in the absence of solvent to selectively produce unsymmetrical ethers in high yields with low catalyst loading. No symmetrical ethers are generated in the reactions. The etherification of a chiral secondary benzyl alcohol

  报道了一种由亚硫酸氢钠催化的醇制备不对称醚的有效方法。该方法能够在不存在溶剂的情况下将伯，仲和叔苄醇与脂肪醇直接脱水，从而以高收率和低催化剂负载选择性地生产不对称醚。反应中不生成对称的醚。手性仲苄醇与丁醇的醚化仅产生外消旋醚，表明该反应涉及碳正离子中间机理。
• Nucleophilic Alkoxylations of Unactivated Alkyl Olefins and α‐Methyl Styrene by Photoredox Catalysis
  作者：Fabienne Seyfert、Mathis Mitha、Hans‐Achim Wagenknecht

  DOI：10.1002/ejoc.202001533

  日期：2021.2.5

  The photoredox catalytic addition of alcohols to non‐activated terminal alkyl olefins is obtained by the use of N,N‐diisobutylamino‐phenylphenothiazine. Its excited state redox potential is sufficiently high to promote the photoreduction.

  通过使用N，N-二异丁基氨基-苯基吩噻嗪可以将醇类光氧化还原催化加成到未活化的末端烷基烯烃上。其激发态氧化还原电势足够高以促进光还原。
• Compounds and Methods of Arylmethylation (Benzylation) As Protection For Alcohol Groups During Chemical Synthesis
  申请人：Dudley Gregory

  公开号：US20100324323A1

  公开（公告）日：2010-12-23

  A process for benzylating an alcohol includes mixing 2-benzyloxy-1-methylpyridinium triflate in an aromatic hydrocarbon solvent having a predetermined boiling point; adding an acid scavenger to the mixture; combining the alcohol to be benzylated with the mixture; reacting the alcohol with the 2-benzyloxy-1-methylpyridinium triflate by heating above ambient temperature to generate the benzylated alcohol; and separating the benzylated alcohol from the mixture.

  一种苯甲基化醇的过程包括将2-苄氧基-1-甲基吡啶三氟甲烷磺酸盐与具有预定沸点的芳香族烃溶剂混合；向混合物中加入酸清除剂；将待苯甲基化的醇与混合物结合；通过加热至高于室温使醇与2-苄氧基-1-甲基吡啶三氟甲烷磺酸盐反应以生成苯甲基化醇；并从混合物中分离苯甲基化醇。
• BiBr3, an efficient catalyst for the benzylation of alcohols: 2-phenyl-2-propyl, a new benzyl-type protecting group
  作者：Bernard Boyer、El-Mehdi Keramane、Jean-Pierre Roque、André A Pavia

  DOI：10.1016/s0040-4039(00)00304-x

  日期：2000.4

  The benzylation of aliphatic alcohols with various benzylic alcohols has been achieved in the presence of BiBr3 under mild conditions. 2-Phenylpropan-2-ol proved to be the most efficient and can be considered as a novel protecting group. (C) 2000 Elsevier Science Ltd. All rights reserved.
• Manufacture of ethers of phenylmethylcarbinol and its homologues
  申请人：DISTILLERS CO YEAST LTD

  公开号：US02248518A1

  公开（公告）日：1941-07-08