diethyl-(E)-1-propyl-2-propyl-ethenylphosphonate | 37175-22-7

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机膦酸及其衍生物
• 英文名称: diethyl-(E)-1-propyl-2-propyl-ethenylphosphonate
• 英文别名: diethyl (1-propyl-pent-1-enyl)phosphonate；Diethyl 1-propylpenten-1-yl-phosphonate；(E)-4-diethoxyphosphoryloct-4-ene
• CAS: 37175-22-7
• 化学式: C₁₂H₂₅O₃P
• 分子量: 248.302
• InChiKey: MGZMEAAXCHCEOI-VAWYXSNFSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.1
• 重原子数：
  16
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  35.5
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  1-辛炔 以 4-辛炔 为溶剂， 以82%的产率得到diethyl-(E)-1-propyl-2-propyl-ethenylphosphonate
  参考文献：
  名称：

  Process for the production of unsaturated phosphonic ester

  摘要：

  在钯配合物催化剂存在下，乙炔化合物与二级磷酸酯反应产生一个不饱和的膦酸酯。

  公开号：

  US05693826A1

文献信息

• Stereoselective Synthesis of (E) or (Z) α-Alkenylphosphonates<i>via</i>α-Stannylated Phosphonates
  作者：N. Mimouni、E. About-Jaudet、N. Collignon、Ph. Savignac

  DOI：10.1080/00397919108021594

  日期：1991.12

  Abstract α-lithiostannylalkylphosphonates react with aldehydes with the complete elimination of the organotin moiety. The stereoselective formation of the (E) or (Z) α-alkenylphosphonates is closely dependent on the tin substituent.

  摘要 α-硫代锡烷基膦酸锂与醛反应，完全消除有机锡部分。(E) 或 (Z) α-烯基膦酸酯的立体选择性形成与锡取代基密切相关。
• Metallo-phosphorylation of alkynes: reaction of alkynes with Cp2Zr(1-butene)(PR3) and chlorophosphateElectronic supplementary information (ESI) available: experimental procedures and NMR data. See http://www.rsc.org/suppdata/cc/b3/b308595c/
  作者：Chunbo Lai、Chanjuan Xi、Chao Chen、Mingming Ma、Xiaoyin Hong

  DOI：10.1039/b308595c

  日期：——

  Reaction of alkynes with Cp2ZrBu2 and chlorophosphate in the presence PR3 to form zircono-alkenylphosphonates, which can be converted into various β-functionalized alkenylphosphonates.

  在PR3存在下，炔烃与Cp2ZrBu2和氯磷酸盐反应生成锆-烯基膦酸酯，这些产物可转化为多种β-官能化的烯基膦酸酯。
• NiCl₂-Catalyzed Hydrophosphinylation
  作者：Patrice Ribière、Karla Bravo-Altamirano、Monika I. Antczak、Jennifer D. Hawkins、Jean-Luc Montchamp

  DOI：10.1021/jo050096l

  日期：2005.5.1

  A new nickel-based catalytic system has been developed for phosphorus-carbon bond formation. The addition of alkyl phosphinates to alkynes is catalyzed by nickel chloride in the absence of added ligand. The reaction generally proceeds in high yields, even with internal alkynes, which were poor substrates in our previously reported palladium-catalyzed hydrophosphinylation of alkyl phosphinates. The method is useful for the preparation of H-phosphinate esters and their derivatives. The one-pot synthesis of various important organophosphorus compounds is also demonstrated. The reaction can be conducted with microwave heating.
• US5693826A
  申请人：——

  公开号：US5693826A

  公开（公告）日：1997-12-02
• Process for the production of unsaturated phosphonic ester
  申请人：Director-General Of Agency Of Industrial Science And Technology

  公开号：US05693826A1

  公开（公告）日：1997-12-02

  An unsaturated phosphonic ester is produced by reaction of an acetylene compound with a secondary phosphite in the presence of a palladium complex catalyst.

  在钯配合物催化剂存在下，乙炔化合物与二级磷酸酯反应产生一个不饱和的膦酸酯。